Amino Tadalafil ntụ ntụ emeputa CAS No.: 385769-84-6 98% ịdị ọcha min.maka ihe mgbakwunye
Ngwa ngwaahịa
| Aha ngwaahịa | Amino Tadalafil |
| Aha ọzọ | (6R,12aR) -2-Amino-6- (1,3-benzodioxol-5-yl) -2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[ 3,4-b] indole-1,4-dione; AminoTadalafil (6R,12Ar) -2-Amino-6-(1,3-Benzodioxol-5-Yl) -2,3,6,7,12,12A -Hexahydropyrazino[1',2':1,6]Pyrido[3,4-B]Indole-1,4-Dione;(6R,12aR) -2-Amino-6-(benzo[d] [1,3] ]dioxol-5-yl)-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indol-1,4-dione;(6R) ,12aR) -2-amino-6- (benzo [d][1,3]dioxol-5-yl) -2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3] ,4-b]indole-1,4(6H,7H)-dione |
| CAS Mba. | 385769-84-6 |
| Usoro ihe omimi | C21H18N4O4 |
| Ibu molekụla | 390.39 |
| Ịdị ọcha | 98.0% |
| Ọdịdị | Na-acha ọcha na-acha ọcha ntụ ntụ |
| Ngwa | Ihe mgbakwunye nri nri |
Ntinye ngwaahịa
Amino Tadalafil bụ ngwakọta yiri Tadalafil, yana ụfọdụ ndị na-arụ ọrụ na nhazi ya na-anọchi anya amino dị iche iche.Ọ bụ ihe mgbochi PDE5 ma nwee mmetụta ọgwụ ọgwụ yiri Tadalafil.A na-eji ya eme ihe maka ọgwụgwọ nwoke erectile dysfunction (ED).E jiri ya tụnyere Tadalafil, Amino Tadalafil na-eji nwayọọ nwayọọ na-eme ka metabolism dị n'ime ahụ, ya mere ọ nwere ike inwe mmetụta na-adịgide adịgide.
Njirimara
(1) Nhọrọ dị elu: Amino Tadalafil nwere nhọrọ dị elu maka PDE5, yana mmekọrịta dị elu maka PDE5 karịa ụdị PDE ndị ọzọ.Nke a pụtara na Amino Tadalafil nwere ike igbochi ọrụ nke enzyme PDE5 nke ọma, na-akwalite mmụba ọbara n'ime akụkụ ọmụmụ nwoke na imeziwanye ihe mgbaàmà nke nrụrụ erectile (ED).
(2) Mmetụta na-adịgide adịgide: Amino Tadalafil na-eme ka metabolism dị nwayọọ n'ime ahụ, nke na-enye ya ohere ịmepụta mmetụta ọgwụ ogologo oge, na-adịgide adịgide ruo awa 36.Nke a na-eme Amino Tadalafil ọgwụ ọgwụgwọ ED na-eme ogologo oge, nke na-adịghị mkpa ka a na-ewere ya ugboro ugboro.
(3) Mmetụta ole na ole: Amino Tadalafil nwere mmetụta ole na ole ma e jiri ya tụnyere Tadalafil, dị ka isi ọwụwa, na nhụjuanya eriri afọ.N'ihi nhọrọ ya dị elu, Amino Tadalafil nwere ike izere mmekọrịta ya na ụdị PDE ndị ọzọ, na-ebelata mmetụta nke mmetụta.
(4) Atụmanya ngwa ngwa: Na mgbakwunye na ịgwọ ED, Amino Tadalafil nwekwara ike iji na-agwọ ọrịa ndị ọzọ dị ka ọbara mgbali elu pulmonary arterial.Nke a na-eme Amino Tadalafil nwere atụmanya ngwa ngwa n'ọdịnihu.
Ngwa
Amino Tadalafil bụ onyinye emepụtara n'afọ ndị na-adịbeghị anya, nke nwere usoro yiri Tadalafil, ma ụfọdụ ndị nọ n'usoro ya na-anọchi anya amino dị iche iche.Ka ọ dị ugbu a, Amino Tadalafil akwadobeghị maka iji ọgwụ eme ihe, ya mere ngwa ya na ngalaba ahụike dị oke oke.Otú ọ dị, ụfọdụ nnyocha egosiwo na ogige a nwere ikike dị ukwuu maka itinye.
Amino Tadalafil bụ onye na-emechi PDE5, nke nwere mmetụta ọgwụ yiri nke Tadalafil.Ọ nwere ike imeziwanye ihe mgbaàmà nke nrụrụ erectile (ED) site n'ịkwalite mmụba ọbara n'ime akụkụ ọmụmụ nwoke site na igbochi ọrụ nke enzyme PDE5.E jiri ya tụnyere Tadalafil, Amino Tadalafil na-eme ka metabolism dị nwayọọ na ahụ, nke nwere ike inwe mmetụta na-adịgide adịgide.Nke a na-eme Amino Tadalafil nwere ikike dị ukwuu na ọgwụgwọ ED.
Tụkwasị na nke ahụ, a pụkwara iji Amino Tadalafil na-agwọ ọrịa ụfọdụ ndị ọzọ, dị ka ọbara mgbali elu nke pulmonary arterial.Ụfọdụ nnyocha egosila na ndị na-egbochi PDE5 nwere ike ịgbasa arịa ọbara pulmonary, si otú ahụ na-emeziwanye ihe mgbaàmà nke ndị ọrịa nwere ọbara mgbali elu pulmonary arterial.N'ihi na Amino Tadalafil nwere mmetụta ọgwụ ọgwụ yiri ya dị ka Tadalafil, a pụkwara iji ya na-emeso ọbara mgbali elu nke pulmonary arterial.
N'ozuzu, Amino Tadalafil nwere nnukwu ngwa ngwa, ma a na-achọkwu ule ụlọ ọgwụ iji chọpụta nchekwa na ịdị irè ya.Ọ bụrụ na ule ndị a na-emepụta ihe dị mma, Amino Tadalafil nwere ike ịghọ ọgwụ ọhụrụ maka ọgwụgwọ ED na ọbara mgbali elu nke pulmonary, na-enye ọtụtụ nhọrọ ọgwụgwọ maka ndị dọkịta na ndị ọrịa.
