Onye na-emepụta ntụ ntụ Nefiracetam Nọmba CAS: 77191-36-7 99% ịdị ọcha nkeji maka ihe mgbakwunye
Vidiyo Ngwaahịa
Usoro Ngwaahịa
| Aha ngwaahịa | Nefiracetam |
| Aha ọzọ | n-(2,6-dimethylphenyl)-2-oxo-1-pyrrolidineacetamide;NEFIRACETAM; 2-oxo-1-pyrrolidinylaseticacid, 2,6-dimethylanilide; dm9384; n-(2,6-dimethylphenyl)-2-oxo-1-pyrrolidineacetamid;DM-9384,(2-(2-Oxopyrrolidin-1-yl)-N-(2,6-dimethylphenyl)-acetamide); DMMPA |
| Nọmba CAS | 77191-36-7 |
| Usoro molekụla | C14H18N2O2 |
| Ibu molekụla | 246.3 |
| Ịdị ọcha | 99.0% |
| Ọdịdị | Ntụ ntụ ọcha |
| Nkwakọ ngwaahịa | 25 kg/gbọmgbọm |
| Ngwa | nootropic |
Okwu mmeghe ngwaahịa
Nefiracetam so n'ezinụlọ piracetam, otu ọgwụ a maara maka ihe ndị na-eme ka ọgụgụ isi dịkwuo mma. E mepụtara Nefiracetam na mbụ na mmalite afọ 1980 ma dọta uche ngwa ngwa n'ihi usoro pụrụ iche ya nke ime ihe na ojiji ọgwụgwọ nwere ike. A na-eche na ngwakọta agbụrụ a na-emetụta ndị na-ahụ maka akwara ozi na ndị na-anabata ya n'ụbụrụ, na-akwalite ikike nghọta ka mma. Nefiracetam na-emetụta ọkwa ụbụrụ nke acetylcholine, isi ihe na-ahụ maka ncheta, mmụta, na ọrụ nghọta. Site n'ịgbanwe ndị na-anabata acetylcholine, nefiracetam na-akwalite nkwukọrịta dị n'etiti akwara ozi, si otú a na-eme ka synaptic plasticity dịkwuo mma ma na-eme ka nchekwa dị mma. Na mgbakwunye, nefiracetam na-emekọrịta ihe na ndị na-anabata gamma-aminobutyric acid (GABA) iji nyere aka dozie ọnọdụ neurotransmitter. Site n'imetụta ndị na-ahụ maka mkpali na ndị na-egbochi ihe, nefiracetam na-enyere aka ịnọgide na-arụ ọrụ ụbụrụ kacha mma, si otú a na-eme ka ilekwasị anya, nlebara anya, na arụmọrụ nghọta zuru oke dịkwuo mma.
atụmatụ
(1) Ịdị ọcha dị elu: Nefiracetam nwere ike inweta ngwaahịa dị ọcha dị elu site na usoro mmepụta dị mma. Ịdị ọcha dị elu pụtara nnweta bioavailability ka mma na obere mmeghachi omume ọjọọ.
(2) Nchekwa: Nchekwa dị elu, obere mmeghachi omume ọjọọ.
(3) Ịkwụsi Ike: Nefiracetam nwere ezigbo nkwụsi ike ma nwee ike ịnọgide na-arụ ọrụ na mmetụta ya n'okpuru gburugburu ebe obibi na ọnọdụ nchekwa dị iche iche.
Ngwa
Nefiracetam bụ ihe sitere na piracetam nke na-eme ka mmiri ghara ịdị n'ahụ, nke a na-ewerekarị dị ka ihe na-akpata nchọpụta nke ọwa calcium n'ime ahụ na mbufe na-apụtaghị ìhè nke ihe mgbaàmà mkpali dị ka ihe na-egbochi akụkụ nke ọwa calcium ion. Ebe njikọ Glycine nke onye nnata NDMA. Site na mmetụta ya na cortex cerebral, nefiracetam nwere ike ime ka ikike nghọta dịkwuo mma ma gbochie nsogbu mmụta na ncheta. Ọ nweghị ihe onwunwe nke onye nnata muscarinic ma ọ bụ ihe ndị na-emegide ya, ọ naghịkwa egbochi ọrụ acetylcholinease. Ya mere, a na-enweta mmetụta mgbochi-amnestic na nke na-akwalite ncheta site na imeziwanye ntọhapụ nke acetylcholine na cortex cerebral.
