Onye Mmepụta Mitoquinone Bromide Nọmba CAS: 336184-91-9 25% ịdị ọcha nkeji. Maka ihe mgbakwunye
Usoro Ngwaahịa
| Aha ngwaahịa | Mitoquinone Bromide |
| Aha ọzọ | mitoquinone bromide Mito-Q MitoQ mitoquinone mitoquinone cation (10-(4,5-Dimethoxy-2-methyl-3,6-dioxocyclohexa-1,4-dien-1-yl)decyl)triphenylphosphonium bromide DMRUQISFVFDWGE-UHFFFAOYSA-M 10-(6'-ubiquinolyl)decyltriphenylphosphonium J-690299 [10-(4,5-Dimethoxy-2-methyl-3,6-dioxo-1,4-cyclohexadien-1-yl)decyl]triphenyl-phosphonium Bromide |
| Nọmba CAS | 336184-91-9 |
| Usoro molekụla | C37H44O4BrP |
| Ibu molekụla | 663.6 |
| Ịdị ọcha | Pasentị iri abụọ na ise |
| Ọdịdị | Ntụ ntụ odo odo ma ọ bụ nke na-acha odo odo |
| Nkwakọ ngwaahịa | 1kg/akpa, 25kg/gbọmgbọm |
| Ngwa | Ihe Ndị E Ji Arụ Ọrụ Maka Nri Mgbakwunye |
Okwu mmeghe ngwaahịa
Mitoquinone bromide bụ ihe atụ nke Coenzyme Q10 nke egosiri na ọ nwere ọrụ antioxidant dị ike. Mitoquinone, nke a makwaara dị ka MitoQ, bụ ụdị pụrụ iche nke Coenzyme Q10 (CoQ10) nke na-elekwasị anya kpọmkwem ma na-agbakọta na mitochondria, ebe ike nke sel ahụ. N'adịghị ka antioxidants nkịtị nke nwere ike inwe nsogbu ịbanye na membrane mitochondrial, a na-emepụta Mitoquinone ka ọ ruo organelle dị mkpa a nke ọma ebe ọ na-egosipụta mmetụta antioxidant dị ike ya. Bromide bụ ion charge na-adịghị mma na usoro kemịkalụ Br⁻. Ọ bụ ihe dị mkpa na ọtụtụ mmeghachi omume kemịkalụ, ọkachasị na mmeghachi omume SN2 ebe ọ nwere ike ịrụ ọrụ dị ka nucleophile ma ọ bụ ionizing radical. A na-elekwasị anya na Mitoquinone bromide na mitochondria site na njikọ covalent na lipophilic triphenylphosphine cation. N'ihi nnukwu ike mitochondrial membrane, cation ahụ na-agbakọta ruo ugboro 1,000 karịa na mitochondria karịa antioxidants ndị na-abụghị ebumnuche dịka Coenzyme Q ma ọ bụ analogs ya, na-eme ka akụkụ antioxidant ahụ nwee ike igbochi lipid peroxidation ma chebe mitochondria site na mmebi oxidative. Site n'igbochi mmebi oxidative nke mitochondrial, ọ na-egbochi ọnwụ nke mkpụrụ ndụ. Mitoquinone bromide nwere ike ịbụ ihe na-eme ka oxidation nke mitochondrial oriri dịkwuo mma.
atụmatụ
(1) Ịdị ọcha dị elu: Mitoquinone bromide nwere ike inweta ngwaahịa dị ọcha dị elu site na usoro mmepụta dị mma. Ịdị ọcha dị elu pụtara nnweta bioavailability ka mma na obere mmeghachi omume ọjọọ.
(2) Nchekwa: Nchekwa dị elu, obere mmeghachi omume ọjọọ.
(3) Ịkwụsi Ike: Mitoquinone bromide nwere ezigbo nkwụsi ike ma nwee ike ịnọgide na-arụ ọrụ na mmetụta ya n'okpuru gburugburu ebe obibi na ọnọdụ nchekwa dị iche iche.
Ngwa
N'ihe gbasara ịka nká, mbelata ọrụ mitochondrial na mkpokọta mmebi oxidative bụ isi ihe na-akpata ịka nká. Mmetụta antioxidant ezubere iche nke mitoquinones na-eme ka ha bụrụ ndị siri ike maka ihe ndị a na-eme iji kwalite ịka nká na ogologo ndụ. Na mgbakwunye, ihe nchebe neuroprotective ya nwere ike igbu oge mbelata nghọta nke metụtara afọ, na-enye ụzọ nwere ike isi nọgide na-enwe ike nghọta n'oge usoro ịka nká. Mitoquinone adọtawokwa uche maka ikike antioxidant ya n'ọhịa nlekọta akpụkpọ ahụ. A na-ekpughe akpụkpọ ahụ mgbe niile na nrụgide gburugburu ebe obibi ma nwee ike ibute mmebi oxidative. Site n'iji ike nke mitochondrial quinones eme ihe, enwere ike nweta agba ntorobịa na nke na-egbuke egbuke.
