Onye na-emepụta ntụ ntụ J-147 Nọmba CAS: 1146963-51-0 99.0% ịdị ọcha nkeji maka ihe mgbakwunye
Usoro Ngwaahịa
| Aha ngwaahịa | 2,2,2-Trifluoroacetic acid 1-(2,4-DiMethylphenyl)-2-[(3-Methoxyphenyl)Methylene]hydrazide] |
| Aha ọzọ | J-147, J147 |
| Nọmba CAS | 1146963-51-0 |
| Usoro molekụla | C18H17F3N2O2 |
| Ibu molekụla | 350.33 |
| Ịdị ọcha | 99% |
| Ọdịdị | Ntụ ntụ ọcha |
| Nkwakọ ngwaahịa | 1kg kwa akpa |
| Ngwa | nootropics |
Okwu Mmalite Ngwaahịa
J-147 bụ ihe na-echebe ụbụrụ nke na-arụ ọrụ nke ọma n'ọnụ nke sitere na curcumin, ihe na-arụ ọrụ na turmeric. N'adịghị ka curcumin, ọ na-agafe ihe mgbochi ọbara-ụbụrụ nke ọma. N'ime ha, J-147 na-arụ ọrụ site na ijikọ na ATP synthase. Mmepụta ATP gabigara ókè na-ejikọta ya na usoro ịka nká. Na mgbakwunye na mmụba nke ọkwa nke ndị na-ahụ maka akwara ozi NGF na BDNF, J-147 nwere ike ijikwa nke a. Na mgbakwunye, J-147 na-egbochi monoamine oxidase B na dopamine transporter. Na-akwalite uto ụbụrụ site na ịbawanye ọkwa nke ihe na-eme ka akwara na-eto (NGF) na ihe na-eme ka ụbụrụ na-enweta neurotrophic (BDNF). Nke kachasị mkpa, J-147 nwere ike ịkwalite uto nke mkpụrụ ndụ akwara ọhụrụ, melite ikike mmụta na ncheta ụbụrụ, ma melite ọrụ nghọta.
atụmatụ
(1) Ịdị ọcha dị elu: J-147 nwere ike inweta ngwaahịa dị ọcha dị elu site na usoro mmepụta dị mma. Ịdị ọcha dị elu pụtara nnweta bioavailability ka mma na obere mmeghachi omume ọjọọ.
(2) Nchekwa: A chọpụtala na J-147 dị mma maka ahụ mmadụ.
(3) Ịkwụsi ike: J-147 nwere ezigbo nkwụsi ike ma nwee ike ịnọgide na-arụ ọrụ na mmetụta ya n'okpuru gburugburu ebe obibi na ọnọdụ nchekwa dị iche iche.
(4) Ọ dị mfe ịmịkọrọ: Ahụ mmadụ nwere ike ịmịkọrọ J-147 ngwa ngwa, banye n'ọbara site na eriri afọ, ma kesaa ya na anụ ahụ na akụkụ ahụ dị iche iche.
Ngwa
J-147 bụ ihe mejupụtara sịntetik nke usoro ọrụ ya bụ isi gụnyere mmụba mitochondrial, si otú a na-eme ka mmepụta ike dịkwuo mma na ọkwa sel. Emebere J-147 iji mee ka ikike ụbụrụ dịkwuo mma idozi ma chebe onwe ya pụọ na mmebi metụtara afọ site na imeziwanye ọrụ mitochondrial. Na mgbakwunye, J-147 na-egosipụta nnukwu ihe mgbochi mkpali na antioxidant, na-eme ka mmetụta neuroprotective ya dịkwuo mma. J-147 nwere ike ịkwalite uto nke mkpụrụ ndụ akwara ọhụrụ, melite ikike mmụta na ncheta ụbụrụ, ma melite ọrụ nghọta.
