7,8-Dihydroxyflavone (7,8-DHF) onye na-emepụta ntụ ntụ CAS No .: 38183-03-8 98.0% ịdị ọcha min.maka ihe mgbakwunye
Ngwa ngwaahịa
| Aha ngwaahịa | 7,8-Dihydroxyflavone |
| Aha ọzọ | 7,8-DIHYDROXYFLAVONE; 7,8-dihydroxy-2-phenyl-4-benzopyrone; DIHYDROXYFLAVONE, 7,8-(RG); 7,8-Dihydroxyflavone hydrate; 7,8-dihydroxy-2-phenyl-1-benzopyran-4-otu |
| CAS Mba. | 38183-03-8 |
| Usoro ihe omimi | C15H10O4 |
| Ibu molekụla | 254.24 |
| Ịdị ọcha | 98.0% |
| Ọdịdị | Acha odo odo ntụ ntụ |
| Ngwa | Ihe mgbakwunye nri nri |
Ntinye ngwaahịa
7,8-Dihydroxyflavone, nke a makwaara dị ka 7,8-DHF, bụ flavonoid sitere n'okike dị n'ụdị osisi dị iche iche, gụnyere Tridacna tridacna.Amara maka akụrụngwa antioxidant na neurotrophic, otu n'ime akụkụ kachasị adọrọ mmasị nke 7,8-dihydroxyflavone bụ ikike ya iji kwado ahụike ụbụrụ yana ịkwalite ọrụ ọgụgụ isi.Nnyocha na-egosi na ogige a na-arụ ọrụ dị ka neurotrophin dị ike, na-akpali uto na nlanarị nke neurons na ụbụrụ.Nnyocha na anụmanụ ụlọ nyocha egosila na 7,8-DHF na-eme ka ncheta na ikike mmụta dịkwuo mma.Site n'ịkwalite nguzobe nke njikọ synapti ọhụrụ na ịkwalite nkwurịta okwu n'etiti mkpụrụ ndụ ụbụrụ, ihe a na-ekwe nkwa imeghe ikike nghọta anyị.Na mgbakwunye, 7,8-dihydroxyflavone na-emekọrịta ihe na ndị na-anabata serotonin nke ụbụrụ, nke na-etinye aka na nhazi ọnọdụ.Site n'ịgbanwe ndị nnabata ndị a, ọ nwere ike belata mgbaàmà nke nchekasị na ịda mbà n'obi.
Njirimara
(1) Ịdị ọcha dị elu: 7,8-Dihydroxyflavone nwere ike nweta ngwaahịa dị ọcha site na mmịpụta eke na usoro nrụpụta dị mma.Ịdị ọcha dị elu pụtara bioavailability ka mma yana mmeghachi omume ọjọọ dị ole na ole.
(2) Nchekwa: 7,8-Dihydroxyflavone bụ ngwaahịa sitere n'okike nke egosipụtara na ọ dị mma nye ụmụ mmadụ.N'ime usoro onunu ogwu, ọ nweghị nsí ma ọ bụ mmetụta ọ bụla.
(3) Nkwụsi ike: 7,8-Dihydroxyflavone nwere ezigbo nkwụsi ike ma nwee ike ịnọgide na-arụ ọrụ ya na mmetụta ya n'okpuru ọnọdụ gburugburu ebe obibi na nchekwa dị iche iche.
(4) Ọ dị mfe ịmịkọrọ: 7,8-Dihydroxyflavone nwere ike ịbanye ngwa ngwa site na ahụ mmadụ, banye n'ọbara ọbara site na eriri afọ, ma kesaa n'anụ ahụ na akụkụ dị iche iche.
Ngwa
7, 8-DHF, dị ka onye na-arụ ọrụ obere molecule dị irè nke onye na-anabata TrkB, nwere ike ịrụ ọrụ nke nchebe neuron, nrụpụta neuron, usoro synaptic plasticity, wdg. melite mgbaàmà nke mmụta mmetụta uche na oghere ebe nchekwa mbelata, cognitive ikike ibelata, moto ọrụ mbelata na ndị ọzọ mgbaàmà nke ụjọ usoro ọrịa dị ka ọrịa Alzheimer ma ọ bụ agadi anụmanụ ụdị, na ibelata metụtara phenotypes nke echiche ọrịa na anụmanụ buru ibu.Ka ọ dị ugbu a, ka ọ dị ugbu a, ọ nweghị mmetụta dị egwu na-egbu egbu nke 7,8-DHF ahụrụ na anụmanụ nnwale.7,8-DHF nwere nnukwu ikike na uru na mgbochi na ọgwụgwọ nke BDNF/TrkB metụtara.
