1,4-DihydronicotinaMide Riboside production powder CAS No.:19132-12-8 98% ọcha nkeji maka ihe mgbakwunye
Usoro Ngwaahịa
| Aha ngwaahịa | 1,4-DihydronicotinaMide Riboside |
| Aha ọzọ | 1,4-DIHYDRONICOTINAMIDE RIBOSIDE1-[(3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,4-dihydropyridine-3-carboxamideSCHEMBL188493711-[(3R,4S,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-4H-PYRIDINE-3-CARBOXAMIDE |
| Nọmba CAS | 19132-12-8 |
| Usoro molekụla | C11H16N2O5 |
| Ibu molekụla | 256.26 |
| Ịdị ọcha | 98% |
| Ọdịdị | Ntụ ntụ ọcha |
| Nkwakọ ngwaahịa | 1kg/akpa; 25kg/gbamgbam |
| Ngwa | Ihe ndị e ji emeju ihe oriri |
Okwu mmeghe ngwaahịa
1,4-dihydronicotinamide riboside, nke a makwaara dị ka NRH.Ụdị NRH dị ala bụ ihe na-ebute NAD+ siri ike nke na-enyere aka imejupụta ọkwa ya na sel.
Nke mbụ, ọ dị mkpa ịghọta ọrụ NAD+ na-arụ n'ahụ. NAD+ bụ coenzyme nke na-etinye aka na ọtụtụ usoro sel, gụnyere metabolism ike, ndozi DNA, na ngosipụta mkpụrụ ndụ ihe nketa. Ka anyị na-etolite, ọkwa NAD+ anyị na-ebelata, nke a na-etinye aka na usoro ịka nká na ọrịa ndị metụtara afọ. Nke a emeela ka mmasị na-eto eto n'ịchọpụta molekul ndị nwere ike ịkwalite ọkwa NAD+ n'ahụ, na 1,4-dihydronicotinamide riboside bụ otu n'ime molekul ndị dị otú ahụ.
1,4-dihydronicotinamide riboside bụ ihe na-ebute NAD+ nke ọma, nnyocha egosikwala na ọ nwere ike ibuli ọkwa NAD+ nke ọma na mkpụrụ ndụ. Nke a emeela ka e chee na mgbakwunye 1,4-dihydronicotinamide riboside nwere ike inwe ike ọgwụgwọ n'ọtụtụ ọnọdụ ahụike, gụnyere nsogbu metabolic, ọrịa neurodegenerative, na mbelata metụtara ịka nká.
N'eziokwu, e nwere ihe akaebe na-egosi na 1,4-dihydronicotinamide riboside nwere ike ịdị irè karịa molekul nne ya, nicotinamide riboside, na mmụba nke ọkwa NAD+. Nke a bụ n'ihi na 1,4-dihydronicotinamide riboside bụ ihe na-ebelata ike karịa, nke pụtara na ọ ka mma inye electrons na ụzọ njikọta NAD+. N'ihi ya, o nwere ike inye mmanụ ọkụ karịa mmepụta NAD+ cell.
Tinyere ọrụ ya na NAD+ biosynthesis, 1,4-dihydronicotinamide riboside nwekwara ihe ndị na-egbochi ọrịa. Nsogbu oxidative, nke sitere na enweghị nguzozi n'etiti free radicals na antioxidants n'ahụ, na-emetụta ọtụtụ ọrịa, gụnyere kansa, ọrịa obi, na nsogbu neurodegenerative. Site n'ịchụpụ free radicals na ibelata mmebi oxidative, 1,4-dihydronicotinamide riboside nwere ike inye uru ahụike ndị ọzọ karịa ọrụ ya dị ka NAD+ precursor.
atụmatụ
(1) Ịdị ọcha dị elu: 1,4-dihydronicotinamide riboside nwere ike inweta ngwaahịa dị ọcha dị elu site na usoro nrụpụta dị mma. Ịdị ọcha dị elu pụtara nnweta bioavailability ka mma na obere mmeghachi omume ọjọọ.
(2) Nchekwa: 1,4-dihydronicotinamide riboside bụ ngwaahịa ebumpụta ụwa nke egosila na ọ dị mma maka ahụ mmadụ.
(3) Ịkwụsi ike: 1,4-dihydronicotinamide riboside nwere ezigbo nkwụsi ike ma nwee ike ịnọgide na-arụ ọrụ na mmetụta ya n'okpuru gburugburu ebe obibi na ọnọdụ nchekwa dị iche iche.
Ngwa
1,4-Dihydronicotinamide bụ ụdị nicotinamide riboside e belatara. Ọ nwere ike ịdị n'ụdị oxidized na nke e belatara, ọ bụkwa ihe na-ebute ụzọ na NAD (nicotinamide adenine dinucleotide) a chọpụtara ọhụrụ, nke dị ka mgbakwunye, ebe NRH bụ ihe na-ebute NAD+ dị ike ma dịkwa ngwa ngwa karịa NR.
