NRC CAS Mba: 23111-00-4 98.0% ịdị ọcha min.maka mgbochi ịka nká
Ngwa ngwaahịa
| Aha ngwaahịa | Nicotinamide riboside chloride |
| Aha ọzọ | NicotinamideB-DRibosideChloride(WX900111); NicotinamideRiboside.Cl;Nicotimideribosidechloride; Pyridinium, 3- (aminocarbonyl) -1-β-D-ribofuranosyl-, chloride (1: 1); 3-carbamoyl-1- ((2R,3R,4S,5R) -3,4-dihydroxy-5- (hydroxymethyl) tetrahydrofuran-2-yl) pyridin-1-iumchloride; 3-Carbamoyl-1- (β-D-ribofuranosyl) pyridiniumchloride; 3-Carbamoyl-1-beta-D-ribofuranosylpyridiniumchloride |
| CAS Mba. | 23111-00-4 |
| Usoro ihe omimi | C11H15ClN2O5 |
| Ibu arọ molekụla | 290.7 |
| Ịdị ọcha | 98.0% |
| Ọdịdị | Na-acha ọcha na-acha ọcha ntụ ntụ |
| Ngwa | Ihe mgbakwunye nri nri |
Ntinye ngwaahịa
Nicotinamide Riboside Chloride bụ biomolecule na mwepụta nke vitamin B3 nke ahụ mmadụ nwere ike itinye ya na metabolize ka ọ bụrụ mmalite nke coenzyme NAD + (nicotinamide adenine dinucleotide).Coenzyme NAD + na-arụ ọtụtụ ọrụ dị mkpa na ahụ mmadụ, gụnyere metabolism ike cellular, nrụzi DNA na apoptosis cell.
A mụọla nsonaazụ nke Nicotinamide Riboside Chloride nke ukwuu.Ọ nwere ike ịkwalite ọrụ mitochondrial, si otú ahụ na-emeziwanye metabolism ike cellular.Mmụba nke metabolism ike nwere ike ịba uru maka ahụike obi, ntachi obi akwara, na nsogbu metabolic.Na mgbakwunye, Nicotinamide Riboside Chloride kwenyere na ọ na-akwalite mmezi DNA na apoptosis cell, si otú a na-enyere aka igbochi ọrịa cancer na ọrịa ndị ọzọ.
Nicotinamide Riboside Chloride nwekwara ike ịkwalite ọrụ nke usoro ahụ ji alụso ọrịa ọgụ nke mmadụ, na-enyere aka iguzogide nje virus na nje.Nnyocha e mere egosiwo na Nicotinamide Riboside Chloride nwere ike ịkwalite ọrụ nke ụfọdụ mkpụrụ ndụ na-alụso ọrịa ọgụ, gụnyere mkpụrụ ndụ egbu egbu anụ ahụ na sel CD8+ T.Selụ ndị a na-arụ ọrụ dị mkpa n'ịlụso ọrịa ọgụ na etuto ahụ ọgụ.
N'ozuzu, nyocha na Nicotinamide Riboside Chloride ka nọ na mmalite ya na a chọkwuru ọmụmụ ụlọ ọgwụ iji gosi na ọ dị irè na nchekwa.Otú ọ dị, a mụọla mmetụta ndị dị ndụ ya n'ọtụtụ ebe ma kwenyere na ọ nwere ọtụtụ uru ahụike na ọgwụgwọ.
Njirimara
(1) Precursor nke NAD +: Nicotinamide Riboside Chloride bụ ihe mmalite nke nicotinamide adenine dinucleotide (NAD +), coenzyme nke na-arụ ọrụ dị mkpa n'ọtụtụ usoro ndu, gụnyere metabolism ike cell, ndozi DNA na akara cell.Site n'inye isi iyi nke NAD +, Nicotinamide Riboside Chloride nwere ike inye aka melite usoro ndị a ma kwalite ahụike zuru oke.
(2) Mmetụta mgbochi ịka nká: Nicotinamide Riboside Chloride egosila na ọ nwere mmetụta mgbochi ịka nká, karịsịa n'ihe gbasara ọrụ mitochondrial.Nnyocha na-egosi na mgbakwunye Nicotinamide Riboside Chloride nwere ike ịbawanye ọkwa NAD + ma welie mitochondrial biogenesis, nke nwere ike inye aka ịlụso ọdịda afọ metụtara arụ ọrụ cellular ọgụ.
(3) Mmetụta Neuroprotective: Nicotinamide Riboside Chloride egosikwara na ọ nwere mmetụta neuroprotective, na ụfọdụ ọmụmụ na-atụ aro na ọ nwere ike inye aka melite ọrụ ọgụgụ isi ma chebe megide ọrịa akwara ozi dị ka Alzheimer na Parkinson.
(4) Mmetụta dị ntakịrị: Nicotinamide Riboside Chloride achọpụtala na ọ dị mma na nke ọma, yana mmetụta ole na ole kọrọ.Ọ na-emekarị na ụfọdụ nri, dị ka mmiri ara ehi na yist, na-akwado profaịlụ nchekwa ya.
Ngwa
Nicotinamide Riboside Chloride bụ biomolecule a na-amụ nke ọma nke sitere na vitamin B3 ma na-eje ozi dị ka ihe mmalite maka coenzyme NAD + n'ime ahụ, na-arụ ọrụ dị mkpa nke ndu.Ugbu a, mpaghara ngwa ngwa nke Nicotinamide Riboside Chloride gụnyere ọrịa obi na akwara ozi, ọrịa neurodegenerative, ọrịa metabolic, na mgbochi ịka nká.Dịka ọmụmaatụ, Nicotinamide Riboside Chloride nwere ike inye aka melite ọrịa ndị metụtara metabolism dị ka ọrịa obi na ọrịa cerebrovascular, ọrịa shuga, na oke ibu site n'ịba ụba metabolism ike cell na imeziwanye ọrụ mitochondrial.Na mgbakwunye, Nicotinamide Riboside Chloride kwenyere na ọ nwere ike ịlụso ọrịa neurodegenerative ọgụ na mgbochi ịka nká.Nnyocha e mere egosiwo na Nicotinamide Riboside Chloride nwere ike imeziwanye ikike ọgụgụ isi na usoro ụjọ na-arụ ọrụ na oke ndị agadi.
Na mgbakwunye, a na-eji Nicotinamide Riboside Chloride agwọ ọrịa uracil metabolism, nke bụ nsogbu metabolic na-adịghị ahụkebe.
Ka nyocha Nicotinamide Riboside Chloride na-aga n'ihu na-abawanye, atụmanya itinye ya na-abawanye ụba.Dịka ọmụmaatụ, enwere ike iji Nicotinamide Riboside Chloride dị ka ihe enyemaka ọgwụ iji gwọọ ọrịa kansa.Nnyocha egosiwo na Nicotinamide Riboside Chloride nwere ike ịkwalite nrụzi DNA na apoptosis cell, si otú a na-enyere aka igbochi ọrịa cancer na ọrịa ndị ọzọ.Ọzọkwa, Nicotinamide Riboside Chloride nwere ike ime ka ọrụ nke sistemu ahụ ji alụso ọrịa ọgụ dịkwuo elu, na-enyere aka iguzogide nje virus na nje.Ngwa ndị a nwere ike ime Nicotinamide Riboside Chloride otu n'ime ebe nyocha dị ugbu a.
Ọzọkwa, usoro njikọ kemịkalụ nke Nicotinamide Riboside Chloride na-akawanye mma mgbe niile, ọnụ ahịa mmepụta ya na-ebelata, nke na-enyekwa ohere dị ukwuu maka itinye ya na ngalaba ahụike.Ya mere, a na-atụ anya Nicotinamide Riboside Chloride ka ọ bụrụ biomolecule nwere atụmanya ngwa sara mbara n'ọdịnihu.
