Galantamine Hydrobromide ntụ ntụ emeputa CAS No.: 1953-04-4 98% ịdị ọcha min. maka ihe mgbakwunye
Ngwa ngwaahịa
| Aha ngwaahịa | Galantamine hydrobromide |
| Aha ọzọ | Galanthamine hydrobromide; Galantamine HBr; Galanthamine HBr; (4aS,6R,8aS) -4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6H-Benzofuro[3a,3,2-ef] [2] benzazepin- 6-ol, Hydrobromide |
| CAS Mba. | 1953-04-4 |
| Usoro ihe omimi | C17H21NO3.HBr |
| Ibu arọ molekụla | 368.27 |
| Ịdị ọcha | 98.0% |
| Ọdịdị | ọcha na-acha ọcha ntụ ntụ |
| Nkwakọ ngwaahịa | 1kg / akpa 10kgs, 25kgs / drum |
| Ngwa | nootropics |
Ntinye ngwaahịa
Galantamine hydrobromide bụ benzazepine sitere na bulbs na ifuru nke narcissus, osmanthus, ma ọ bụ canna. Ọ bụkwa ihe mgbochi cholinesterase nke ọnụ. Dị ka njikọ maka ndị na-anabata nicotinic acetylcholine, ejirila ya mee ihe iji kwalite ọrụ neurocognitive. Ọrụ ya bụ ịsọ mpi na ngbanwe na-egbochi acetylcholinesterase, si otú ahụ na-abawanye mkpokọta acetylcholine. Mgbe etinyere ya n'ọbara, galantamine hydrobromide na-abanye ngwa ngwa n'akụkụ dị iche iche nke ahụ, gụnyere ụbụrụ. Ọ na-ejikọta na nicotinic acetylcholine receptors, na-eme mgbanwe mgbanwe na mmụba acetylcholine ntọhapụ. Ọ na-arụkwa ọrụ site na ịsọ mpi na ịtụgharị mmetụta nke ndị na-egbochi cholinesterase. Site na igbochi cholinesterase, ọ na-egbochi nkwụsị nke acetylcholine, si otú ahụ na-abawanye ọkwa na ogologo oge nke neurotransmitter dị ike. Galantamine nwekwara ike imeziwanye mmụta na ebe nchekwa, gbochie mbufụt nke ụbụrụ, ma nọgide na-enwe ọkwa dị elu nke neurotransmitters site n'ịkwado iguzosi ike n'ezi ihe nke neurons na synapses.
Njirimara
(1) Ịdị ọcha dị elu: Galantamine hydrobromide nwere ike ịbụ ngwaahịa dị ọcha site na nhazi usoro mmepụta ihe. Ịdị ọcha dị elu pụtara bioavailability ka mma yana mmeghachi omume ọjọọ dị ole na ole.
(2) Nchekwa: egosila na Galantamine hydrobromide dị mma maka ahụ mmadụ.
(3) Nkwụsi ike: Galantamine hydrobromide nwere ezigbo nkwụsi ike ma nwee ike ịnọgide na-arụ ọrụ ya na mmetụta ya n'okpuru ebe dị iche iche na ọnọdụ nchekwa.
Ngwa
Dị ka ihe mgbakwunye nri, galantamine hydrobromide nwere ike melite ebe nchekwa, nsụhọ, na ike ịrụ ọrụ kwa ụbọchị. Ọ na-arụ ọrụ site na iweghachi nguzozi nke ụfọdụ ihe ndị sitere n'okike (neurotransmitters) na ụbụrụ, nke na-abawanye ọsọ nke nhazi ebe nchekwa ma na-eme ka njide nkọwa na eziokwu dịkwuo mma. Na mgbakwunye, galantamine hydrobromide ozugbo ma ọ bụ na-apụtaghị ìhè na-emetụta neuroplasticity. Ọ na-akpali plastik synapti site na ịgbalite microglia na astrocytes. Galantamine na-enye nchebe antioxidant megide nrụgide oxidative nke radicals efu kpatara.
