Coluracetam ntụ ntụ emeputa CAS No .: 135463-81-9 99% ịdị ọcha min. maka ihe mgbakwunye
Video ngwaahịa
Ngwa ngwaahịa
Aha ngwaahịa | Coluracetam |
Aha ọzọ | MKC-231; 2-oxo-N- (5,6,7,8-tetrahydro-2,3-dimethyl-furo [2,3-b] quinolin-4-yl) -1-pyrrolidineacetamide |
CAS Mba. | 135463-81-9 |
Usoro ihe omimi | C19H23N3O3 |
Ibu arọ molekụla | 341.4 |
Ịdị ọcha | 99.0% |
Ọdịdị | Ọcha ntụ ntụ |
Ngwa | Ihe mgbakwunye nri nri |
Ntinye ngwaahịa
Coluracetam, onye òtù agbụrụ agbụrụ nke ogige nootropic, nke a makwaara dị ka MKC-231, bụ ihe na-emepụta ihe na-eme ka ahụ dịkwuo mma na mmetụta neuroprotective. Coluracetam na-arụ ọrụ site n'ịgbanwe usoro cholinergic. A na-eche na ọ na-abawanye ọkwa nke acetylcholine, isi ihe na-ebute ụbụrụ na ụbụrụ nwere njikọ chiri anya na mmụta na ọrụ nchekwa. Coluracetam na-eme nke a site n'ịbawanye ọnụọgụ na ọrụ nke ndị na-ebugharị choline, si otú ahụ na-eme ka ntọhapụ nke acetylcholine dịkwuo mma ma na-eme ka akara ngosi dị n'etiti neurons. Ụfọdụ nchọpụta mbụ na ọmụmụ anụmanụ na-atụ aro na Coluracetam nwere mmetụta neuroprotective na-eme ka ahụ dịkwuo mma. Ụfọdụ nchọpụta ndị ọzọ achọpụtala na Coluracetam nwere mmetụta ụfọdụ na-emeziwanye na nsogbu ebe nchekwa na ụdị AD.
Njirimara
(1) Ịdị ọcha dị elu: A na-akwado Coluracetam site na iji mmịpụta dị elu na mmepụta usoro iji hụ na ịdị ọcha dị elu. Ịdị ọcha a dị elu na-enyere aka melite bioavailability ma belata ihe omume nke mmeghachi omume ọjọọ.
(2) Nchekwa: A na-ewere Coluracetam dị mma maka mmadụ. Ọnụ ọgụgụ dị ukwuu nke ọmụmụ egosila na ọ nwere obere toxicity na obere mmetụta dị n'ime usoro ọgwụgwọ akwadoro.
(3) Nkwụsi ike: Nkwadebe Coluracetam na-egosipụta nkwụsi ike dị mma ma nwee ike ịnọgide na-arụ ọrụ ha na ịdị irè n'okpuru ebe dị iche iche na ọnọdụ nchekwa. Nkwụsi ike a na-eme ka arụmọrụ kwụsie ike na nke a pụrụ ịdabere na ya ruo ogologo oge.
Ngwa
A na-eji Coluracetam mee ihe ugbu a n'ụdị ngwa dị iche iche ma gosipụta nkwa dị ukwuu n'ọdịnihu. A na-eji ya eme ihe n'ụzọ bụ isi dị ka ihe mgbakwunye nri na-eme ka ọgụgụ isi dịkwuo elu ma ndị mmadụ n'otu n'otu na-achọ imeziwanye ebe nchekwa, itinye uche na ikike mmụta. A na-eche na ikike nke ngwakọta ahụ iji gbanwee usoro cholinergic na-enye aka na mmetụta ya na-eme ka ọgụgụ isi pụta. Tụkwasị na nke ahụ, nchọpụta na-egosi na Coluracetam nwere ike ịnwe ihe ndị na-adịghị mma nke nwere ike inye aka gbochie ịda mbà n'obi nke afọ na ịkwado ahụike ụbụrụ zuru ezu.