5-Aminolevulinic acid phosphate (ALA) onye na-emepụta ntụ ntụ CAS Nọmba: 868074-65-1 98% ọcha nkeji na ọnụahịa kacha mma
Vidiyo Ngwaahịa
Usoro Ngwaahịa
| Aha ngwaahịa | 5-Aminolevulinic acid phosphate |
| Aha ọzọ | 5-amino-4-oxopentanoic acid, phosphoric acid; 5-aminolevulinic acid phosphate,5-ALA phosphate; 5-Amino-4-oxopentanoic acid phosphate; 5-Aminolevulinic acid phosphate; Pentanoic acid, 5-amino-4-oxo-, phosphate |
| Nọmba CAS | 868074-65-1 |
| Usoro molekụla | C5H12NO7P |
| Ibu molekụla | 229.13 |
| Ịdị ọcha | 98.0% |
| Ọdịdị | Ntụ ntụ ọcha ruo na ntụ ọcha na-acha ọcha |
| Ngwa | Ihe Mgbakwunye Nri Ihe Ndị A Na-anaghị Ewu |
Okwu mmeghe ngwaahịa
5-Aminolevulinic acid phosphate, nke a maara dịka ALA phosphate, bụ isi ihe dị n'etiti biosynthesis nke heme, ihe dị mkpa nke hemoglobin, myoglobin na enzymes dị iche iche n'ahụ. A na-emepụta ALA phosphate site na usoro mmeghachi omume enzymatic nke na-eme karịsịa na mitochondria, ebe ike nke mkpụrụ ndụ anyị. A na-emepụta ya site na njikọta nke glycine na succinyl-CoA, nke bụ akụkụ dị mkpa nke ụzọ metabolic anyị. Mmepụta nke heme dị oke mkpa maka ahụike mmadụ ebe molekul a na-arụ ọrụ dị mkpa na njem oxygen, nnyefe elektrọn na mwepụ ihe mkpofu. ALA phosphate bụ nzọụkwụ na-egbochi ọnụego na biosynthesis heme. Site na usoro mgbanwe enzymatic, a na-agbanwe ALA phosphate ka ọ bụrụ porphobilinogen, molekul mbụ nke heme.
atụmatụ
(1) Ịdị ọcha dị elu: Enwere ike inweta phosphate 5-aminolevulinic acid dị ka ngwaahịa dị ọcha dị elu site na usoro nrụpụta dị mma. Ịdị ọcha dị elu pụtara nnweta bioavailability ka mma na obere mmeghachi omume ọjọọ.
(2) Nchekwa: A chọpụtala na phosphate 5-aminolevulinic dị mma maka ahụ mmadụ.
(3) Ịkwụsi ike: 5-Aminolevulinic acid phosphate nwere ezigbo nkwụsi ike ma nwee ike ịnọgide na-arụ ọrụ na mmetụta ya n'okpuru gburugburu ebe obibi na ọnọdụ nchekwa dị iche iche.
Ngwa
5-Aminolevulinic acid phosphate (5-ALA) bụ amino acid eke na ihe na-arụ ọrụ nke dị n'ọtụtụ ebe ná ndụ. Ọ bụ ihe na-ebute ụzọ nke porphyrin compounds na ihe ndabere maka mmeghachi omume biochemical nke chlorophyll, heme na vitamin B12. 5-ALA phosphate bụ ihe sitere na 5-ALA ma ahụ na-amịkọrọ ma jiri ya mee ihe ngwa ngwa. Ntinye ọnụ nke 5-ALA phosphate nwere ike ime ka myoglobin synthase rụọ ọrụ, mee ka myoglobin dịkwuo ngwa ngwa n'ahụ mmadụ, mee ka abụba akwara dịkwuo elu, ma belata abụba. Na mgbakwunye, 5-ALA nwekwara ike ime ka ọrụ mitochondria dịkwuo mma na mkpụrụ ndụ mmadụ, kwalite metabolism, melite arụmọrụ inweta ike, ma belata shuga ọbara na lipids ọbara. Na mmechi, 5-ALA phosphate bara ezigbo uru maka ahụike.
