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Ngwakọta 7P ntụ ntụ emepụtara CAS No.: 1890208-58-8 99% ịdị ọcha min. maka ihe mgbakwunye

Nkọwa dị mkpirikpi:

E gosipụtara ngwakọta 7p iji mee ka uto nke GAP-43-positive axon na ụdị anụmanụ nke mmerụ ahụ akwara optic, na-atụ aro na ọrụ mmepụta neurite nke compound 7p in vitro na-asụgharị n'ime mkpali nke axon regeneration na vivo.


Nkọwa ngwaahịa

Mkpado ngwaahịa

Video ngwaahịa

Ngwa ngwaahịa

Aha ngwaahịa

Ngwakọta 7P

Aha ọzọ

Ngwakọta7P;2-[(2-methoxyphenyl) [(4-methylphenyl) sulfonyl] amino] -N- (4-methoxy-3-pyridinyl) acetamide;

2- (N- (2-methoxyphenyl) -4-methylphenylsulfonamido) - N- (4-methoxypyridin-3-yl) acetamide.

CAS Mba.

1890208-58-8

Usoro ihe omimi

C22H23N3O5S

Ibu arọ molekụla

441.51

Ịdị ọcha

99.0%

Ọdịdị

Ọcha ntụ ntụ

Ngwa

Nootropic

Ntinye ngwaahịa

Ngwakọta 7P na-ezo aka na ngwakọta organic nke nwere atom carbon asaa. Na kemịkalụ organic, carbon bụ ihe dị mkpa n'ihi na ọ nwere ike ịmepụta njikọ kwụsiri ike na atom ndị ọzọ, gụnyere carbon carbon, iji mepụta ụmụ irighiri ihe dị mgbagwoju anya. Ụmụ irighiri ihe ndị a nwere ike inwe ihe dị iche iche na ọrụ dị iche iche, na-eme ka ogige ndị sitere na carbon bụrụ ihe mgbochi nke ndụ. N'ụdị anụmanụ nke mmerụ ahụ akwara optic, e gosipụtara 7p compound iji mee ka uto nke GAP-43-positive axon, na-atụ aro na ọrụ uto neurite nke compound 7p in vitro sụgharịrị n'ime mkpali nke axonal regeneration na vivo. Ngwakọta 7P ntụ ntụ bụ ọcha na-acha ọcha na-acha ọcha na-emepụta dị ka ihe nchịkọta tandem maka njirimara nke abụọ na-eme ihe na-eme ihe na-eme ka thromboxane antagonist inhibitors. N'ezie, onyinye 7p gosipụtara nhọrọ maka prostaglandin I2 synthase (PTGIS, CYP8A1) metụtara thromboxane synthase (CYP5A1). Ngwakọta nootropic 7P ntụ ntụ na-akwalite uto nke Gap-43-positive axon, si otú ahụ na-akpali akpali axonal regeneration n'ime ahụ. Emebere mgbagwoju anya 7p dị elu iji melite nhazi, meziwanye ọnọdụ ma nyere aka ịlụ ọgụ ike ọgwụgwụ. Ọ na-egbochikwa ikuku oxidation nke ụbụrụ ma na-enyere aka ịlụso mmebi ụbụrụ ọgụ nke ịṅụ mmanya na-akpata.

Njirimara

结构图

(1) Ịdị ọcha dị elu: Ngwakọta 7P nwere ike nweta ngwaahịa dị ọcha site na usoro mmepụta ihe a nụchara anụcha. Ịdị ọcha dị elu pụtara bioavailability ka mma yana mmeghachi omume ọjọọ dị ole na ole.

(2) Nchekwa: Compound 7P egosila na ọ dị mma maka ahụ mmadụ.

(3) Nkwụsi ike: Compound 7P nwere ezigbo nkwụsi ike ma nwee ike ịnọgide na-arụ ọrụ ya na mmetụta ya n'okpuru ebe dị iche iche na ọnọdụ nchekwa.

Ngwa

Ngwakọta 7p na-akwalite uto neurite nke neurons bụ isi emebere nke sitere na hippocampus, cortex cerebral, na retina ma na-ebute mmeghari akwara optic na ụdị anụmanụ nke mmerụ ahụ akwara optic. Ọ na-eme ka nhazi ahụ dịkwuo mma, na-agwọ mmebi ụbụrụ metụtara mmanya na-aba n'anya, ma na-egbochi oxidation gburugburu ụbụrụ. Ọ na-enyekwa aka melite ọnọdụ na ịlụso ike ọgwụgwụ ọgụ.


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