Kedu ihe bụ Salidroside, kedukwa ka o si enyere gị aka?

Salidroside A makwaara ya dị ka (4-hydroxy-phenyl)-β-D-glucopyranoside, nke a makwaara dị ka saldroside na rhodiola extract. Enwere ike iwepụta ya site na Rhodiola rosea ma ọ bụ mepụta ya site na aka. Salidroside bụ ihe na-egbochi mkpụrụ ndụ akwara site na iwepụ ROS na igbochi apoptosis nke mkpụrụ ndụ.

Rhodiola rosea bụ osisi ahịhịa na-eto ruo mgbe ebighị ebi nke na-etokarị n'ebe oyi na-atụ nke ukwuu, kpọrọ nkụ, anoxia, radieshon ultraviolet siri ike, na nnukwu ọdịiche okpomọkụ n'etiti ehihie na abalị n'ịdị elu nke mita 1,600 ruo 4,000. O nwere ike ime mgbanwe gburugburu ebe obibi na ịdị ndụ siri ike nke ukwuu.

Salidroside - Ọgwụ mgbochi oxidant

Salidroside bụ ihe na-egbochi ọrịa nke sitere n'okike nke nwere ike igbupụ ụdị oxygen reactive (ROS), gbochie apoptosis, ma chebe mkpụrụ ndụ akwara. Ọ nwere ike imeziwanye ikike nchekwa antioxidant nke akpụkpọ ahụ site na ịgbalite sistemụ enzyme antioxidant intracellular, dịka superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), wdg.

Oke calcium dị n'ime sel bụ otu n'ime ihe ndị na-akpata apoptosis neuronal. Ihe a na-ewepụta na Rhodiola rosea na salidroside nwere ike ibelata mmụba nke ọkwa calcium na-enweghị sel nke nrụgide oxidative na-akpata ma chebe mkpụrụ ndụ cortical mmadụ site na glutamate. na apoptosis nke hydrogen peroxide kpatara. Salidroside nwere ike igbochi mkpali microglial nke lipopolysaccharide kpatara, gbochie mmepụta NO, gbochie ọrụ nitric oxide synthase (iNOS) inducible, ma belata ọkwa TNF-α na IL-1β., IL-6.

Salidroside na-egbochi NADPH oxidase 2/ROS/mitogen-activated protein kinase (MAPK) na ihe na-achịkwa nzaghachi nke mmepe na mmebi DNA 1 (REDD1)/ihe mgbaru ọsọ nke rapamycin (mTOR)/p70 ribosome. Ụzọ mgbaama protein S6 kinase na-eme ka usoro mgbaama protein nke dabere na AMP/silent information regulator 1, RAS homologue gene member A/MAPK na PI3K/Akt rụọ ọrụ.

Uru nke Salidroside

1. Mmetụta nhazi ụzọ abụọ: Rhodiola rosea na-ahazi ihe niile dị mma n'ahụ ma nwee mmetụta nhazi ụzọ abụọ nke imezu ihe ndị na-adịghị mma na ibelata oke ibu. Site n'ịchịkwa ọrụ nke sistemụ akwara, sistemụ endocrine na sistemụ metabolic, enwere ike iweghachi shuga dị n'ọbara, abụba dị n'ọbara, ọbara mgbali elu na ọrụ obi na akwara ụbụrụ ka ọ dịghachi mma.

2. Nhazi dị irè nke sistemụ akwara: iwepụ nrụgide nke ndị mmadụ nke ọma, mee ka usoro akwara etiti dị mma, melite ụra na iwe, obi ụtọ ma ọ bụ ịda mbà n'obi; melite nlebara anya ma melite ncheta. Mee ka ụbụrụ dị ọhụrụ, belata ọnụego njehie, melite arụmọrụ ọrụ na ọmụmụ ihe, ma gbochie ọrịa Alzheimer.

3. Ọgwụ mgbochi ike ọgwụgwụ: Rhodiola rosea nwere mmetụta obi, nke nwere ike ime ka oge ọrụ nkịtị nke ụbụrụ na ahụ dịkwuo elu ma gbasaa ikike ibu nke akwara ụbụrụ na akwara ahụ. Ọ nwere mmetụta dị ukwuu n'igbochi na ịgwọ ọrịa ike ọgwụgwụ yana ịnọgide na-enwe ike na ume siri ike ruo ogologo oge.

4. Mgbochi radieshọn na mgbochi etuto: Salidroside nwere ike ime ka ọnụego mgbanwe nke T lymphocytes na ọrụ nke phagocytes dịkwuo elu nke ọma, melite mgbochi ọrịa, gbochie uto etuto ahụ, mụbaa mkpụrụ ndụ ọbara ọcha, iguzogide radieshon microwave, ma gwọọ ndị ọrịa kansa mgbe ọgwụgwọ redio na ihe ndị ọzọ gasịrị. Ọ nwere mmetụta dị mma maka ndị na-adịghị ike mgbe ha rịasịrị ọrịa.

5. Mgbochi hypoxia: Rhodiola rosea nwere ike ibelata oke oriri oxygen n'ahụ, melite nnabata ụbụrụ na hypoxia, ma n'otu oge ahụ mee ka ikike ibu oxygen nke ọbara dịkwuo elu, mee ka iguzogide ọrịa dịkwuo elu, ma weghachite anụ ahụ ndị nwere ọrịa ngwa ngwa.

6. Mmetụta dị n'ahụ akwara dị nro nke mmadụ: Ọ na-akpata ụkwara ume ọkụ site na spasm akwara dị nro. Rhodiola rosea nwere ike ibelata spasm akwara dị nro nke ọma ma chịkwaa mmegharị akwara dị nro nke eriri afọ. Ọ na-enwe mmetụta doro anya na ụkwara ume ọkụ, bronchitis, phlegm, afọ ntachi, wdg.

7. Mmetụta na ọrịa ogbu na nkwonkwo: Ihe ọjọọ atọ dị ka ifufe, oyi, na mmiri mmiri na-akpata ọrịa ogbu na nkwonkwo. Ọtụtụ nnwale ahụike egosila na Rhodiola rosea nwere ike ịchụpụ ikuku, iguzogide oyi, ma wepụ ihe mgbu. Ọ na-enwe mmetụta doro anya na ọzịza nkwonkwo. Ọzịza na mmetụta mgbochi.

8. Mgbochi ịka nká: Rhodiola rosea nwere ike igbu oge ịka nká nke mkpụrụ ndụ, mee ka ọrụ SOD dịkwuo elu n'ahụ, ma gbochie mmepụta nke lipofuscin na ụdị oxygen na-emegharị ahụ. Mee ka metabolism na mmepụta nke mkpụrụ ndụ dịkwuo mma ma melite ike nke mkpụrụ ndụ. Na mgbakwunye, ọ nwekwara mmetụta mara mma na nlekọta akpụkpọ ahụ.

Ubi Salidroside na Nlekọta Akpụkpọ Ahụ

N'ihe gbasara nlekọta akpụkpọ ahụ, saldroside nwere ike iguzogide mmebi ultraviolet ma wepụ ihe ndị na-emebi emebi nke mitochondria na-emepụta. Mmetụta antioxidant na mgbochi mbufụt ya nwere ike ime ka akpụkpọ ahụ ka mma, belata wrinkles, ma mee ka akpụkpọ ahụ dị ka nke nwata.

Rhodiola rosea nwere ike ibelata ọrụ acid phosphatase na ngwaahịa ikpeazụ nke lipid peroxide (LPO) site n'ịbawanye ọrụ nke enzymes metụtara antioxidant (SOD superoxide dismutase, GSH-Px glutathione peroxidase na CAT) ọdịnaya na ọdịnaya MDA, si otú a na-eme ka ikike ahụ nwere ịchụpụ radicals free, na-ebelata ogo peroxidation nke biofilms, na ichebe sel na anụ ahụ site na mmebi radicals free.

Gbochie foto akpụkpọ ahụ

Salidroside nwere ike ibelata mmebi nke ihe ndị dị n'èzí dịka collagen ma kwalite uto nke fibroblasts, si otú a na-eme ka akpụkpọ ahụ na-agbanwe agbanwe, na-egbu oge mmalite nke wrinkles akpụkpọ ahụ, ma mezuo ebumnuche nke iguzogide fotoage.

Ịcha ọcha

Salidroside nwere ike ibelata mmepụta melanin site na igbochi ọrụ tyrosinase. Tyrosinase bụ enzyme dị mkpa maka mmepụta melanin. Salidroside nwere ike ijikọ na tyrosinase ma belata ọrụ ya, si otú a belata mmepụta melanin.

Salidroside nwekwara ike igbochi mmepụta melanin site n'ịhazi ụzọ mgbaàmà na melanocytes, dịka ụzọ mgbaàmà MITF. MITF bụ isi ihe na-eme ka mkpụrụ ndụ melanocytes dị na melanocytes, nke na-achịkwa ngosipụta nke enzymes metụtara mmepụta melanin dịka tyrosinase. Salidroside nwere ike ibelata ngosipụta nke MITF, si otú a belata mmepụta melanin.

Mgbochi mkpali

Salidroside nwere ike ibelata mmeghachi omume mkpali nke ụzarị ultraviolet na-akpata, rụzie mkpụrụ ndụ akpụkpọ ahụ mebiri emebi, ma kwalite mmụba na ndozi akpụkpọ ahụ.

Ọnọdụ mmepụta saldroside ugbu a

1) Na-adaberekarị na mwepụta osisi

Rhodiola rosea bụ ihe e ji emepụta saldroside. Dịka ụdị osisi ahịhịa na-adịru ogologo oge, Rhodiola rosea na-etokarị n'ebe nwere oke oyi, anoxia, akọrọ na nnukwu ọdịiche okpomọkụ n'etiti ehihie na abalị n'ogo nke mita 1600-4000. Ọ bụ otu n'ime osisi ọhịa dị larịị. China bụ otu n'ime ebe ndị Rhodiola rosea na-emepụta ihe n'ụwa, mana àgwà ndụ nke Rhodiola rosea pụrụ iche. Ọ bụghị naanị na ọ siri ike ịkọ ihe n'ụzọ aka, kamakwa mmepụta nke ụdị ọhịa dị obere nke ukwuu. Ugbu a, oghere ọchịchọ kwa afọ maka Rhodiola rosea dị elu ruo tọn 2,200.

2) Njikọta kemịkalụ na ịgbakọ mmiri ọgwụ

N'ihi obere ọdịnaya na oke ọnụ ahịa mmepụta ihe dị na osisi, na mgbakwunye na ụzọ mwepụta eke, ụzọ mmepụta saldroside gụnyekwara ụzọ mmepụta kemịkalụ, ụzọ ịgba mmiri ihe dị ndụ, wdg. N'ime ha, ka teknụzụ ahụ na-aga n'ihu na-eto, ịgba mmiri ihe dị ndụ aghọwo ụzọ teknụzụ kachasị maka nyocha na mmepe na mmepụta nke saldroside. Ugbu a, Suzhou Mailun enwetala nsonaazụ nyocha na mmepe ma nweta mmepụta ụlọ ọrụ mmepụta ihe.

Radiation bụ akụkụ a na-apụghị izere ezere nke ndụ anyị kwa ụbọchị, a na-ejikwa ya eme ihe mgbe niile n'ịchọpụta na ịgwọ ọrịa. Agbanyeghị, mmebi nke radieshon na-akpata n'anụ ahụ na mkpụrụ ndụ mmadụ enweghị ike ileghara anya. Ya mere, ịchọta ihe nchebe radieshon dị irè, nke na-adịghị egbu egbu ma ọ bụ nke na-anaghị egbu egbu abụrụla ebe a na-eme nnyocha mgbe niile.

Suzhou Myland Nutraceuticals Inc. bụ ụlọ ọrụ mmepụta ihe nke FDA debanyere aha ya, nke na-enye ntụ ntụ Salidroside dị elu ma dị ọcha.

Na Suzhou Myland, anyị na-agba mbọ inye ngwaahịa kachasị mma na ọnụ ahịa kacha mma. A na-anwale ntụ ntụ Salidroside anyị nke ọma maka ịdị ọcha na ike, na-eme ka ị nweta mgbakwunye dị elu ị nwere ike ịtụkwasị obi. Ma ịchọrọ ịkwado ahụike sel, ịkwalite sistemu ahụ ji alụso ọrịa ọgụ gị ma ọ bụ melite ahụike zuru oke, ntụ ntụ Salidroside anyị bụ nhọrọ zuru oke.

Site na ahụmịhe afọ iri atọ nke teknụzụ dị elu na atụmatụ R&D kachasị mma, Suzhou Myland emepụtala ọtụtụ ngwaahịa asọmpi ma bụrụ ụlọ ọrụ mgbakwunye sayensị ndụ ọhụrụ, mmepụta omenala na ọrụ mmepụta.

Tinyere nke ahụ, Suzhou Myland bụkwa onye nrụpụta nke FDA debanyere aha ya. Akụrụngwa nyocha na mmepe nke ụlọ ọrụ ahụ, ebe mmepụta, na ngwa nyocha ya bụ nke ọgbara ọhụrụ ma na-arụ ọrụ nke ọma, ha nwekwara ike imepụta kemịkalụ site na milligram ruo tọn n'ọkwa, ma na-agbaso ụkpụrụ ISO 9001 na nkọwapụta mmepụta GMP.