Kedu ihe bụ Salidroside na kedu ka ọ ga-esi nyere gị aka?

Salidroside a makwaara dị ka (4-hydroxy-phenyl) -β-D-glucopyranoside, nke a makwaara dị ka salidroside na rhodiola wepụ. Enwere ike wepụ ya na Rhodiola rosea ma ọ bụ na-arụ ọrụ artificially. Salidroside bụ antioxidant eke na-echebe mkpụrụ ndụ akwara site n'ịkpachapụ ROS na igbochi apoptosis cell.

Rhodiola rosea bụ osisi herbaceous perennial nke na-etolite na mpaghara oyi dị oke, nkụ, anoxia, radieshon ultraviolet siri ike, yana nnukwu ọdịiche dị n'etiti ehihie na abalị na elu 1,600 ruo 4,000 mita. O nwere ngbanwe gburugburu ebe obibi siri ike na ike.

Salidroside - Antioxidant

Salidroside bụ antioxidant eke nwere ike ịchụpụ ụdị oxygen na-emeghachi omume (ROS), gbochie apoptosis, ma chebe mkpụrụ ndụ akwara. Ọ nwere ike imeziwanye ikike nchebe nke anụ ahụ site na ịgbalite sistemu enzyme antioxidant intracellular, dị ka superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), wdg.

Ibubiga calcium intracellular bụ otu n'ime isi ihe na-ebute apoptosis neuronal. Mwepụta Rhodiola rosea na salidroside nwere ike belata mmụba nke ọkwa calcium n'efu intracellular nke nrụgide oxidative kpatara ma chebe mkpụrụ ndụ cortical mmadụ site na glutamate. na hydrogen peroxide sitere na apoptosis. Salidroside nwere ike igbochi lipopolysaccharide na-akpata microglial activation, na-egbochi mmepụta NO, na-egbochi ọrụ nitric oxide synthase (iNOS), ma belata TNF-a na IL-1β. IL-6 ọkwa.

Salidroside na-egbochi NADPH oxidase 2 / ROS / mitogen-activated protein kinase (MAPK) na nzaghachi nzaghachi nke mmepe na DNA mmebi 1 (REDD1) / mammalian target of rapamycin (mTOR) / p70 ribosome protein S6 kinase akara ụzọ na-eme ka AMP-adabere. protein kinase/onye na-ahụ maka ozi nzuzo 1, RAS homologous gene onye otu ezinụlọ A/MAPK na PI3K/Akt ụzọ akara.

Uru Salidroside

1. Mmetụta na-achịkwa ụzọ abụọ: Rhodiola rosea na-achịkọta ihe niile dị mma n'ime ahụ ma nwee mmetụta na-achịkwa ụzọ abụọ nke ime ka erughị eru na ibelata oke. Site n'ịchịkwa ọrụ nke usoro ụjọ ahụ, usoro endocrine na usoro metabolic, shuga ọbara, lipids ọbara, ọbara mgbali na ọrịa obi na cerebrovascular nwere ike iweghachite ọkwa nkịtị.

2. Usoro dị irè nke usoro ụjọ ahụ: kpochapụ nsogbu ndị mmadụ n'ụzọ dị irè, dozie usoro nhụjuanya nke etiti, meziwanye ụra na mgbakasị ahụ, obi ụtọ ma ọ bụ ịda mbà n'obi; kwalite nlebara anya ma kwalite ebe nchekwa. Mee ka ụbụrụ dị ọhụrụ, belata ọnụego njehie, melite ọrụ na ọmụmụ ihe, ma gbochie ọrịa Alzheimer.

3. Mgbochi ike ọgwụgwụ: Rhodiola rosea nwere mmetụta cardiotonic, nke nwere ike ime ka ogologo oge na-arụ ọrụ nkịtị nke ụbụrụ na ahụ ma gbasaa ikike nke ụbụrụ ụbụrụ na uru ahụ. Ọ nwere mmetụta dị ịrịba ama na igbochi na ịgwọ ọrịa ike ọgwụgwụ na ịnọgide na-enwe ike na ume ike ruo ogologo oge.

4. Mgbochi radieshon na mgbochi tumor: Salidroside nwere ike n'ụzọ dị irè na-amụba mgbanwe ọnụego nke T lymphocytes na ọrụ nke phagocytes, welie immunity, na-egbochi etuto uto, na-amụba ọbara ọcha mkpụrụ ndụ, iguzogide microwave radieshon, na-agwọ ọrịa cancer mgbe radiotherapy na ndị ọzọ. Ọ nwere mmetụta mmezigharị inyeaka dị mma maka ndị na-adịghị ike anụ ahụ mgbe ọrịa gasịrị.

5. Anti-hypoxia: Rhodiola rosea nwere ike ibelata ọnụ ọgụgụ oriri oxygen zuru oke nke anụ ahụ, mee ka ụbụrụ na-anabata hypoxia, ma n'otu oge ahụ na-eme ka ikuku oxygen na-ebu ọbara, mee ka ọrịa ahụ na-eguzogide ọgwụ ngwa ngwa, na-agbake ngwa ngwa anụ ahụ ndị ọrịa. .

6. Mmetụta dị n'ahụ ahụ mmadụ dị nro: Asthma na-akpata site na spasm dị nro. Rhodiola rosea nwere ike belata spasm nke anụ ahụ dị nro ma na-ahazi mmegharị ahụ nke eriri afọ dị nro. Ọ nwere mmetụta doro anya na ụkwara ume ọkụ, bronchitis, phlegm, afọ ntachi, wdg.

7. Mmetụta na ọrịa ogbu na nkwonkwo: Ọrịa ogbu na nkwonkwo na-akpata site n'ihe ọjọọ atọ nke ifufe, oyi, na iru mmiri. Ọnụ ọgụgụ dị ukwuu nke ule ụlọ ọgwụ egosila na Rhodiola rosea nwere ike ịchụpụ ifufe, gbochie oyi, ma wepụ ihe mgbu. Ọ na-enwe mmetụta doro anya na ọzịza nkwonkwo. Ọzịza na mmetụta mgbochi.

8. Mgbochi ịka nká: Rhodiola rosea nwere ike igbu oge ịka nká cell, mụbaa ọrụ SOD n'ime ahụ, ma gbochie mmepụta nke lipofuscin intracellular na ụdị oxygen na-emeghachi omume. Mee ka cell metabolism na njikọ aka ma melite ume cell. Na mgbakwunye, ọ nwekwara ịma mma na mmetụta nlekọta anụ ahụ.

Salidroside & Mpaghara Nlekọta anụ ahụ

N'ihe gbasara nlekọta anụ ahụ, salidroside nwere ike iguzogide mmebi ultraviolet ma wepụ free radicals nke mitochondria mepụtara. Mmetụta antioxidant ya na mgbochi mkpali nwere ike ime ka ọnọdụ akpụkpọ ahụ dịkwuo mma, belata wrinkles, ma mee ka akpụkpọ ahụ dị obere.

Rhodiola rosea nwere ike belata ọrụ phosphatase acid na ngwaahịa ikpeazụ decomposition nke lipid peroxide (LPO) site n'ịbawanye ọrụ nke enzymes metụtara antioxidant (SOD superoxide dismutase, GSH-Px glutathione peroxidase na CAT) ọdịnaya na ọdịnaya MDA, si otú ahụ na-eme ka ike nke anụ ahụ dịkwuo elu. iji kpochapu radicals n'efu, ibelata ogo peroxidation nke biofilms, na ichekwa sel na anụ ahụ na mmebi nke radical free.

Gbochie ịse foto akpụkpọ ahụ

Salidroside nwere ike ibelata mbelata nke matrix extracellular dị ka collagen ma kwalite uto nke fibroblasts, si otú ahụ na-eme ka nhịahụ akpụkpọ ahụ dịkwuo mma, na-egbu oge ihe omume nke wrinkles akpụkpọ, na imezu ebumnuche nke iguzogide photoaging.

Na-acha ọcha

Salidroside nwere ike ibelata njikọ melanin site na igbochi ọrụ tyrosinase. Tyrosinase bụ isi enzyme maka njikọ melanin. Salidroside nwere ike jikọta na tyrosinase ma belata ọrụ ya, si otú ahụ belata mmepụta nke melanin.

Salidroside nwekwara ike igbochi njikọ nke melanin site n'ịhazi ụzọ mgbaàmà na melanocytes, dị ka ụzọ akara MITF. MITF bụ isi ihe ederede na melanocytes, nke na-achịkwa okwu nke melanin metụtara enzymes dị ka tyrosinase. Salidroside nwere ike ibelata okwu MITF, si otú ahụ belata njikọ nke melanin.

mgbochi mkpali

Salidroside nwere ike ibelata nzaghachi mkpali nke ụzarị ultraviolet kpatara, rụkwaa mkpụrụ ndụ akpụkpọ ahụ mebiri emebi, ma kwalite mmegharị anụ ahụ na nrụzi.

Ọnọdụ mmepụta salidroside ugbu a

1) tumadi ịdabere na osisi mmịpụta

Rhodiola rosea bụ akụrụngwa nke salidroside. Dị ka ụdị osisi herbaceous perennial, Rhodiola rosea na-etolite na mpaghara nwere oke oyi, anoxia, nkụ na nnukwu ọdịiche dị n'etiti ehihie na abalị na elu 1600-4000 mita. Ọ bụ otu n'ime osisi ala dị larịị. China bụ otu n'ime mpaghara na-emepụta Rhodiola rosea n'ụwa, mana àgwà ndụ nke Rhodiola rosea bụ ihe pụrụ iche. Ọ bụghị naanị na ọ siri ike ịzụlite artificially, ma mkpụrụ nke ụdị ọhịa dị oke ala. Ka ọ dị ugbu a, oghere chọrọ maka Rhodiola rosea kwa afọ ruru tọn 2,200.

2) Chemical njikọ na ndu gbaa ụka

N'ihi ọdịnaya dị ala na ọnụ ahịa mmepụta ihe dị elu na osisi, na mgbakwunye na ụzọ mmepụta eke, usoro mmepụta salidroside na-agụnyekwa usoro njikọ kemịkalụ, usoro ịgba ụka ndu, wdg. N'ime ha, ka nkà na ụzụ na-aga n'ihu na-eto eto, ihe ọkụkụ nke ndu aghọwo ihe bụ isi. ụzọ teknụzụ maka nyocha na mmepe na mmepụta nke salidroside. Ka ọ dị ugbu a, Suzhou Mailun enwetala nsonaazụ nyocha na mmepe wee nweta mmepụta ihe.

Radiation bụ akụkụ a na-apụghị izere ezere nke ndụ anyị kwa ụbọchị ma na-ejikarị eme nchọpụta ahụike na ọgwụgwọ. Otú ọ dị, a pụghị ileghara mmebi nke radieshon kpatara anụ ahụ na sel mmadụ anya. Ya mere, ịchọta ndị ọrụ nchebe nke ọma, ndị na-adịghị egbu egbu ma ọ bụ ndị na-adịghị egbu egbu na-abụkarị ebe nyocha.

Suzhou Myland Nutraceuticals Inc. bụ onye na-emepụta aha FDA nke na-enye ntụ ntụ Salidroside dị elu na nke dị elu.

Na Suzhou Myland anyị na-agba mbọ ịnye ngwaahịa kachasị mma na ọnụ ahịa kacha mma. A na-anwale ntụ ntụ Salidroside anyị nke ọma maka ịdị ọcha na ike, na-eme ka ị nweta mgbakwunye dị elu ị nwere ike ịtụkwasị obi. Ma ịchọrọ ịkwado ahụike cellular, kwalite usoro ahụ ji alụso ọrịa ọgụ ma ọ bụ kwalite ahụike zuru oke, ntụ ntụ Salidroside anyị bụ nhọrọ zuru oke.

Site na ahụmịhe afọ 30 na teknụzụ dị elu na atụmatụ R&D kachasị mma, Suzhou Myland ewepụtala ngwaahịa dị iche iche nke asọmpi wee bụrụ mgbakwunye sayensị ndụ ọhụụ, njikọta omenala na ụlọ ọrụ nrụpụta.

Na mgbakwunye, Suzhou Myland bụkwa onye nrụpụta FDA debanyere aha. Akụrụngwa R&D nke ụlọ ọrụ ahụ, akụrụngwa nrụpụta na ngwa nyocha bụ nke ọgbara ọhụrụ yana ọtụtụ ọrụ, ma nwee ike imepụta kemịkalụ site na milligrams ruo tọn n'ọ̀tụ̀tụ̀, ma na-agbaso ụkpụrụ ISO 9001 na nkọwapụta GMP.