J-147 onye na-emepụta ntụ ntụ CAS No.: 1146963-51-0 99.0% ịdị ọcha min. maka ihe mgbakwunye
Ngwa ngwaahịa
| Aha ngwaahịa | 2,2,2-Trifluoroacetic acid 1- (2,4-DiMethylphenyl) -2-[(3-Methoxyphenyl) Methylene] hydrazide] |
| Aha ọzọ | J-147, J147 |
| CAS Mba. | 1146963-51-0 |
| Usoro ihe omimi | C18H17F3N2O2 |
| Ibu arọ molekụla | 350.33 |
| Ịdị ọcha | 99% |
| Ọdịdị | Ọcha ntụ ntụ |
| Nkwakọ ngwaahịa | 1kg kwa akpa |
| Ngwa | nootropics |
Okwu Mmalite ngwaahịa
J-147 bụ neuroprotectant na-arụ ọrụ nke ọma nke sitere na curcumin, ihe na-arụ ọrụ na turmeric. N'adịghị ka curcumin, ọ na-agafe ihe mgbochi ụbụrụ ọbara nke ọma. N'ime ha, J-147 na-arụ ọrụ site na ijikọ ATP synthase. Mmepụta nke ATP na-ejikọta ya na usoro ịka nká. Na mgbakwunye na ịbawanye ọkwa nke neurotransmitters NGF na BDNF, J-147 nwere ike ịchịkwa nke a. Na mgbakwunye, J-147 na-egbochi monoamine oxidase B na dopamine transporter. Na-akwalite uto ụbụrụ site n'ịbawanye ọkwa nke ihe na-eto eto (NGF) na ụbụrụ neurotrophic factor (BDNF). Nke kachasị mkpa, J-147 nwere ike ịkwalite uto nke mkpụrụ ndụ akwara ọhụrụ, kwalite ikike mmụta na ebe nchekwa ụbụrụ, ma melite ọrụ ọgụgụ isi.
Njirimara
(1) Ịdị ọcha dị elu: J-147 nwere ike nweta ngwaahịa dị elu site na nhazi usoro mmepụta ihe. Ịdị ọcha dị elu pụtara bioavailability ka mma yana mmeghachi omume ọjọọ dị ole na ole.
(2) Safety: J-147 a woyii no adi no kyerɛ sɛ wopɛ sɛ wuhu sɛnea wote nka.
(3) Nkwụsi ike: J-147 nwere ezigbo nkwụsi ike ma nwee ike ịnọgide na-arụ ọrụ ya na mmetụta ya n'okpuru ebe dị iche iche na ọnọdụ nchekwa.
(4) Ọ dị mfe ịnabata: J-147 ahụ mmadụ nwere ike ịbanye ngwa ngwa, na-esi n’eriri eriri afọ banye n’ọbara na-ekesa ma kesaa ya n’anụ ahụ na akụkụ ahụ dị iche iche.
Ngwa
J-147 bụ ihe sịntetik nke usoro ọrụ ya bụ isi na-agụnye nkwalite mitochondrial, si otú ahụ na-ebuli mmepụta ike na ọkwa cellular. Emebere J-147 iji kwalite ikike ụbụrụ imezi yana chebe onwe ya pụọ na mmebi metụtara afọ site na imeziwanye ọrụ mitochondrial. Na mgbakwunye, J-147 na-egosipụta ihe mgbochi mkpali na ihe antioxidant, na-eme ka mmetụta neuroprotective ya dịkwuo elu. J-147 nwere ike ịkwalite uto nke mkpụrụ ndụ akwara ọhụrụ, kwalite ikike mmụta na ebe nchekwa ụbụrụ, ma melite ọrụ ọgụgụ isi.
