Kedu ihe bụ Trigonelline HCl na gịnị kpatara ị ga-eji lekọta?

N'ụwa nke ahụike na ahụike, a na-emekarị ka a na-elekwasị anya na ogige dị iche iche nke nwere uru dị iche iche. Otu ngwakọta nke dọtara uche n'afọ ndị na-adịbeghị anya bụ Trigonelline HCl. Trigonelline hydrochloride bụ alkaloid nke na-emekarị nke a na-ahụ n'ụdị osisi dị iche iche, karịsịa mkpụrụ fenugreek na agwa kọfị. Ọ bụ ihe mmepụta nke amino acid niacin ma mara ya maka nhazi kemịkalụ ya pụrụ iche nke na-enye ya ohere ịmekọrịta usoro ihe ndụ dị iche iche na ahụ. "HCl" n'aha ya na-ezo aka n'ụdị hydrochloride ya, nke na-eme ka ọ dị nro na bioavailability ya, na-eme ka ọ dịkwuo mfe maka ahụ.

Ntinye ngwaahịa

Trigonelline HCl(CAS: 6138-41-6) bụ ntụ ntụ ọcha na-acha ọcha. Trigonelline HCl bụ nnu etolite mgbe mmeghachi omume nke trigonelline na hydrochloric acid gasịrị. Ngwakọta, ụdị nnu na-enwekarị mma solubility na nkwụsi ike. Trigonelline, nke a makwaara dị ka niacin betaine, na aha sayensị ya bụ trimethylxanthine, bụ ngwakọta alkaline nwere nitrogen nke na-egosi dị ka ntụ ntụ ọcha crystalline ma na-agbaze na methanol na mmiri. Trigonelline bụ isi akụrụngwa alkaloid nke fenugreek ma nwee ọtụtụ ihe omume ndu, gụnyere antioxidant, mgbochi mkpali, na ụkpụrụ shuga ọbara. Trigonelline hydrochloride na-egosipụtakwa mmetụta yiri nke ahụ n'ihe gbasara bioactivity, mana ọ nwere ike ịba uru na bioavailability n'ihi ike ya ka mma.

Ngwa ọrụ

Mbelata shuga ọbara

Nnyocha e mere egosiwo na n'ụdị oke ọrịa shuga nke 2, trigonelline nwere ike ibelata shuga ọbara na ọkwa insulin, na-abawanye index sensitivity index, na ịbawanye ibu nke pancreatic, oke ibu nke pancreas na ahụ, na ibu nke pancreas site n'ịkwalite mgbanwe mkpụrụ ndụ beta pancreatic na ibelata nguzogide insulin. . Ọdịnaya insulin, si otú a na-ebelata ọkwa shuga dị n'ọbara.

Mgbochi ịka nká

Nnyocha na-egosi na mgbakwunye trigonelline nwere ike ịbawanye ọkwa NAD + ma mụbaa ọrụ mitochondrial, si otú a na-enyere aka melite usoro ịka nká. Dịka ọmụmaatụ, na nematodes, trigonelline nwere ike belata atrophy muscle n'ihi afọ ma gbasaa ogologo ndụ; na ụmụ oke, trigonelline nwere ike ịkwalite ike akwara nke ọma ma belata ike ọgwụgwụ n'oge ịka nká.

Melite ọrụ ọgụgụ isi

Nnyocha e mere egosiwo na trigonelline nwere ike imeziwanye ebe nchekwa mbelata nke ụmụ oke ịka nká site na igbochi mmepụta nke ihe ndị na-akpata mkpali na ịkwalite ntọhapụ nke neurotransmitters. Tụkwasị na nke ahụ, trigonelline nwekwara ike ime ka ọrụ synapse na-arụ ọrụ na sel neuroblastoma SK-N-SH, nke nwere ike jikọta ya na usoro ya iji meziwanye ebe nchekwa.

Obere lipids ọbara

N'ime oke GK ụdị 2 na-arịa ọrịa shuga, trigonelline belatara ọbara ọbara na ịba ọcha n'anya triglyceride, mbelata ọrụ ịba ọcha n'anya acid synthase, yana ịba ụba carnitine palmitoyltransferase imeju na ọrụ glucokinase.

Ngwa ụlọ ọrụ nke Trigonelline HCl

Trigonelline nwere ọrụ dị iche iche nke anụ ahụ, gụnyere antioxidant, na-ebelata shuga ọbara, na-ekpochapụ radicals free, na-eme ka ọrụ mitochondrial dịkwuo elu, na-abawanye ike anụ ahụ, ibelata mmebi cell, meziwanye ọrụ ọgụgụ isi, wdg Dabere na nke a, Trigonelline HCl na-ejikarị eme ihe na ọgwụ ọgwụ. ụlọ ọrụ, a na-eji ya dị ka ihe na-arụ ọrụ na ọgwụ.

Ebe ị ga-azụta Trigonelline HCl?

N'ime ụwa nri na ahụike ọgbara ọhụrụ, Trigonelline HCl na-anata nlebara anya na-abawanye maka uru ahụike ya dị ukwuu. Dị ka a ndammana eme alkaloid, Trigonelline HCl bụ tumadi amịpụtara si mkpo na ụfọdụ osisi na ọtụtụ-eji na ahụ ike ngwaahịa na ọtọ nri. Site na mmụba nke ndị ahịa maka ihe ndị sitere n'okike, ọchịchọ maka ntụ ntụ Trigonelline HCl dị elu na-arị elu n'ahịa,

Mgbe ị na-azụta Trigonelline HCl, ịdịmma bụ nke kacha mkpa. Ịkwesịrị ijide n'aka na ịzụrụ n'aka onye na-ebubata ngwaahịa a ma ama nke na-enye ngwaahịa dị mma.Mgbe ị na-achọ "trigonelline hydrochloride," jide n'aka na ịlele nyocha na asambodo nke ndị ọzọ iji hụ na ọ dị ọcha na ike ngwaahịa ahụ. Ịgụ nyocha ndị ahịa nwekwara ike inye nghọta maka ịdị irè nke ngwaahịa na ntụkwasị obi nke onye na-ere ahịa.

1. Ogo ngwaahịa

Mgbe ị na-ahọrọ onye na-ebubata ihe, ihe mbụ ị ga-atụle bụ àgwà ngwaahịa ahụ. Nnukwu ịdị ọcha Trigonelline HCl ntụ ntụ na-eme ka ọrụ ndụ ya na ịdị irè ya. The Trigonelline HCl ntụ ntụ nke Suzhou Myland na-enye enwetala ule siri ike iji hụ na ngwaahịa ọ bụla na-agbaso ụkpụrụ mba ụwa ma kwenye na ọ dị mma.

2. Ike mmepụta

Ike mmepụta nke onye nrụpụta na-emetụta kpọmkwem oge na nkwụsi ike nke ọkọnọ. Suzhou Myland nwere ngwá ọrụ mmepụta ihe dị elu na nkà na ụzụ nke nwere ike izute mkpa nke mmepụta ihe dị ukwuu, na-eme ka ndị ahịa nwee ike nweta ngwaahịa ha chọrọ n'oge mgbe ha chọrọ ha.

3. R&D ike

Onye na-ebubata ihe mara mma na-enwekarị otu R&D siri ike nke nwere ike na-aga n'ihu na-emeziwanye ngwaahịa ma mepụta ngwaahịa ọhụrụ. Suzhou Myland chịkọbara ọgaranya ahụmahụ na nyocha na ngwa nke Trigonelline HCl na-enwe ike inye ndị ahịa na ọkachamara oru nkwado na ngwọta.

4. Ọrụ ndị ahịa

Ezi ọrụ ndị ahịa bụ ihe na-enweghị ike ileghara anya mgbe ị na-ahọrọ ndị na-ebubata ya. Suzhou Myland na-elekwasị anya na nkwurịta okwu na ndị ahịa ma nwee ike ịnye ọrụ ahaziri iche dịka mkpa ndị ahịa si dị iji hụ na ndị ahịa nwetara ahụmahụ kachasị mma n'oge usoro ịzụrụ ihe.

5. Asambodo na nnabata

Ịhụ na ndị na-eweta ngwaahịa nwere asambodo dị mkpa na nnabata bụ ihe dị mkpa maka nhọrọ. Suzhou Myland bụ asambodo ISO ma na-agbaso ụkpụrụ GMP (Good Manufacturing Practice), na-ahụ na ngwaahịa ya na-agbaso usoro njikwa mma siri ike n'oge usoro mmepụta.

Dị ka onye na-emepụta Trigonelline HCl ntụ ntụ, Suzhou Myland emeriwo ntụkwasị obi nke ọtụtụ ndị ahịa na ngwaahịa ya dị ọcha na njikwa mma. Ụlọ ọrụ ahụ na-agba mbọ inye ndị ahịa ihe eji eme ihe dị elu ma nyere ha aka ime nke ọma na ụlọ ọrụ ha.

Ịhọrọ onye na-eweta Trigonelline HCl ziri ezi bụ isi ihe iji hụ na ịdịmma ngwaahịa na nchekwa. Suzhou Myland aghọwo nhọrọ a pụrụ ịtụkwasị obi na ụlọ ọrụ na ngwaahịa ya dị oke ọcha, njikwa mma na ọrụ ọkachamara. Ma ị bụ onye na-emepụta ngwaahịa nlekọta ahụike ma ọ bụ ụlọ ọrụ nri, Suzhou Myland nwere ike inye gị ntụ ntụ Trigonelline HCl dị elu iji nyere gị aka ahụike na mmepe ọrụ gị. Maka nkọwa ndị ọzọ, biko gaa na webụsaịtị gọọmentị Suzhou Myland.