Imeghe ihe nzuzo nke Spermidine: Ihe na-arụ ọrụ na ogologo ndụ na ahụike

N'ime afọ ndị na-adịbeghị anya, ndị ọkà mmụta sayensị na-elekwasị anya na ọrụ nke autophagy na-akwalite ahụike na ogologo ndụ. Autophagy, usoro cellular nke na-ewepụ ihe ndị mebiri emebi ma na-emegharị ihe ndị cellular, dị mkpa maka ịnọgide na-enwe homeostasis cellular na ọrụ. Otu ngwakọta nke dọtara uche maka ikike ọ nwere ịkwalite autophagy bụ spermidine, polyamine na-emekarị nke a na-achọta na nri dị iche iche. Edemede a na-enyocha uru spermidine dị, isi nri nri ya kacha mma, yana ọrụ ya na-ekwe nkwa na mgbochi ịka nká.

Kedu ihe bụ Spermidine?

Spermidine bụ polyamine nke na-arụ ọrụ dị mkpa na usoro cellular, gụnyere uto cell, mmụba, na ọdịiche. A na-emepụta ya n'ime ahụ site na amino acid ornithine ma na-etinye aka na ọrụ dị iche iche nke ndu, dị ka DNA stabilization, gene expression, na cellular signaling. Ọ bụ ezie na ahụ anyị na-emepụta spermidine, iri nri nwere ike imetụta ọkwa ya.

Uru nkeSpermidine

Nnyocha egosiwo na spermidine na-enye ọtụtụ uru ahụike, karịsịa n'ihe gbasara ịka nká na ogologo ndụ. Nke a bụ ụfọdụ uru ama ama:

1. Na-akwalite Autophagy: E gosipụtara Spermidine na-ebute autophagy, usoro na-enyere aka ikpochapụ sel na protein ndị mebiri emebi. Site n'ịkwalite autophagy, spermidine nwere ike inye aka chebe onwe ya pụọ ​​​​na ọrịa ndị metụtara afọ ma melite ahụike cellular n'ozuzu ya.

2. Health Cardiovascular: Nnyocha na-egosi na spermidine nwere ike inwe mmetụta nchebe nke obi. Ejikọtala ya na ịrụ ọrụ obi ka mma, mbelata ọbara mgbali, yana obere ihe ize ndụ nke ọrịa obi. Ngwakọta ahụ nwere ike inye aka ịnọgide na-enwe ngbanwe nke arịa ọbara ma belata mbufụt, na-enye aka na ahụike obi ka mma.

3. Neuroprotection: Spermidine egosipụtawo ihe ndị na-adịghị mma, nke nwere ike inye aka na mgbochi nke ọrịa neurodegenerative dị ka Alzheimer na Parkinson. Site n'ịkwalite autophagy, spermidine nwere ike inye aka kpochapụ protein ndị na-egbu egbu na-agbakọta na ụbụrụ, si otú ahụ na-akwado ọrụ ọgụgụ isi na ebe nchekwa.

4. Mmetụta Mgbochi Ọrịa: Ọfụfụ na-adịghị ala ala bụ ihe e ji mara ọtụtụ ọrịa ndị metụtara afọ. E gosipụtara Spermidine ka ọ na-arụ ọrụ mgbochi mkpali, nwere ike ibelata ihe ize ndụ nke ọnọdụ dị ka ọrịa ogbu na nkwonkwo, ọrịa shuga, na ụfọdụ ọrịa cancer.

5. Ahụike Metabolic: Nnyocha na-egosi na spermidine nwere ike ịrụ ọrụ n'ịhazi metabolism na ịkwalite njikwa ibu dị mma. A na-ejikọta ya na mmetụta insulin ka mma yana glucose metabolism, nke dị mkpa maka igbochi ọrịa metabolic.

Spermidine na mgbochi ịka nká

Ọchịchọ maka ngwọta mgbochi ịka nká emeela ka mmasị na spermidine mụbaa. Ka anyị na-aka nká, arụmọrụ nke autophagy na-ebelata, na-eduga n'ịchịkọta akụkụ cellular mebiri emebi. Site n'ịkwalite autophagy, spermidine nwere ike inye aka igbochi ụfọdụ mmetụta ịka nká.

Ọtụtụ nchọpụta egosila na mgbakwunye spermidine nwere ike ịgbatị ndụ nke ụdị dị iche iche, gụnyere yist, ikpuru, na ijiji. Ọ bụ ezie na ọmụmụ ihe mmadụ ka dị na nwata, nchọpụta mbụ ahụ na-ekwe nkwa. Ndị na-eme nchọpụta kwenyere na spermidine nwere ike inye aka mee ka ahụike dịkwuo mma-oge ndụ a na-eji na ahụike dị mma-site n'igbu oge mmalite nke ọrịa ndị metụtara afọ.

Isi mmalite nke spermidine

Ọ bụ ezie na spermidine dị ka ihe mgbakwunye nri, a pụkwara inweta ya site na nri dị iche iche. Ịgbakwunye nri bara ụba spermidine n'ime nri gị bụ ụzọ ebumpụta ụwa iji kwalite ọkwa gị nke onyinye a bara uru. Nke a bụ ụfọdụ isi mmalite spermidine kacha mma:

1. Nri fermented: Ngwaahịa ndị fermented dị ka natto (soybean fermented), miso, na sauerkraut bụ ezigbo isi mmalite nke spermidine. Usoro ịgba ụka ahụ na-eme ka bioavailability nke spermidine dịkwuo mma, na-eme ka ọ dịkwuo mfe maka ahụ.

2. Mkpụrụ ọka: Mkpụrụ zuru oke dị ka germ wheat, oat, na osikapa agba aja aja nwere ụbara na spermidine. Ịtinye ọka ndị a na nri gị nwere ike inye isi iyi nke carbohydrates dị mma yana uru spermidine.

3. Legumes: Agwa, lentil, na peas abụghị nanị nnukwu protein na fiber kama ọ nwekwara nnukwu spermidine. Ha bụ ihe dị iche iche nwere ike ịgbakwunye na efere dị iche iche.

4. Akwụkwọ nri: Ụfọdụ akwụkwọ nri, karịsịa ndị nọ n'ezinụlọ cruciferous, dị ka broccoli, kọlịflawa, na Brussels pulite, bụ ezigbo isi iyi nke spermidine. Akwụkwọ ndụ akwụkwọ ndụ dị ka akwụkwọ nri na kale na-esokwa rie nri spermidine.

5. Mkpụrụ osisi: Ụfọdụ mkpụrụ osisi, gụnyere oroma, apụl, na ube oyibo, nwere spermidine, n'agbanyeghị na ọ dị ntakịrị ma e jiri ya tụnyere nri ndị ọzọ. Ịtinye mkpụrụ osisi dị iche iche na nri gị nwere ike inyere gị aka inweta nri kwesịrị ekwesị.

6.Mushrooms: Ụfọdụ ụdị ero, dị ka shiitake na maitake, mara na ọ nwere spermidine. Ha nwere ike ịbụ mgbakwunye na-atọ ụtọ na nri mgbe ha na-enye uru ahụike.

Myland Nutraceuticals Inc. bụ onye na-emepụta aha FDA nke na-enye nnukwu mma, nnukwu ọcha Spermidine ntụ ntụ.

Na Myland Nutraceuticals Inc., anyị na-agba mbọ ịnye ngwaahịa kachasị mma na ọnụ ahịa kacha mma. Spermidine ntụ ntụ anyị na-enweta ule siri ike maka ịdị ọcha na ike, na-eme ka ị nweta mgbakwunye mma ị nwere ike ịtụkwasị obi. Ma ị na-achọ ịkwado ahụike cellular, kwalite usoro ahụ ji alụso ọrịa ọgụ, ma ọ bụ kwalite ọdịmma gị n'ozuzu ya, Spermidine ntụ ntụ bụ nhọrọ zuru oke maka gị. 

Site na ahụmịhe afọ 30 na teknụzụ dị elu na atụmatụ R&D kachasị mma, Myland Nutraceuticals Inc. ewepụtala ngwaahịa dị iche iche nke asọmpi dị ka mgbakwunye sayensị ndụ ọhụrụ, njikọta omenala na ụlọ ọrụ nrụpụta.

Na mgbakwunye, Myland Nutraceuticals Inc. bụkwa onye nrụpụta aha FDA. Akụrụngwa R&D nke ụlọ ọrụ ahụ, akụrụngwa nrụpụta na ngwa nyocha bụ nke ọgbara ọhụrụ yana ọtụtụ, ma nwee ike imepụta kemịkalụ n'otu milligram ruo ton ma na-agbaso ụkpụrụ ISO 9001 na nkọwapụta GMP.

Mmechi

Spermidine na-apụta dị ka onye mmekọ dị ike n'ọchịchọ ahụike na ogologo ndụ. Ikike ya iji kwalite autophagy, na-akwado ahụike obi obi, na inye mmetụta neuroprotective na-eme ka ọ bụrụ ihe bara uru ịtụle n'ihe gbasara ịka nká. Site n'itinye nri bara ụba spermidine n'ime nri gị, ị nwere ike ịkwalite ọkwa nke polyamine a bara uru ma nwee ike ịkwalite ahụike na ọdịmma gị n'ozuzu ya.

 

Ka nyocha na-aga n'ihu, ọdịnihu na-ele anya maka spermidine dị ka ụzọ ebumpụta ụwa iji kwalite ogologo ndụ na ịlụso ọrịa ndị metụtara afọ ọgụ. Ma site na isi nri nri ma ọ bụ mgbakwunye, spermidine nwere ike ijide mkpịsị ugodi maka imeghe ahụike ka ogologo ndụ.