Ịkwado ọkwa cholesterol dị mma dị mkpa maka ahụike obi na ahụike zuru oke. Cholesterol dị elu nwere ike ịkpata nsogbu ahụike dị iche iche, gụnyere ọrịa obi na ọrịa strok. Ọ bụ ezie na enwere ike ịnye ọgwụ iji chịkwaa cholesterol, mgbanwe ndụ dị mfe nwekwara ike rụọ ọrụ dị mkpa n'ibelata cholesterol n'ụzọ nkịtị. Iri nri dị mma, itinye aka na mgbatị ahụ mgbe niile, ịchịkwa nchekasị, ụra zuru oke, na isonye na atụmatụ mgbakwunye nri bụ ihe niile dị mkpa iji nọgide na-enwe ọkwa cholesterol dị mma. Site n'ime mgbanwe ndị a dị nta na usoro ị na-eme kwa ụbọchị, ị nwere ike imezi ahụike obi gị ma kwado ọdịmma gị n'ozuzu ya.
Cholesterol bụ ihe na-egbu egbu, nke a na-ahụ na sel ọ bụla nke ahụ anyị. Ọ bụ ihe dị mkpa dị mkpa iji mepụta hormones, vitamin D, na ihe ndị na-enyere aka mgbaze. Ọ bụ ezie na cholesterol dị mkpa ka ahụ anyị rụọ ọrụ nke ọma, ọkwa cholesterol dị elu nwere ike imerụ ahụ ike anyị.
Ahụ anyị na-emepụta cholesterol n'ime imeju na eriri afọ, anyị na-erikwa cholesterol site na nri ụfọdụ, dị ka anụ, anụ ọkụkọ, na ngwaahịa mmiri ara ehi zuru oke. Enwere ụdị cholesterol abụọ: lipoprotein dị elu (HDL), nke a na-akpọkarị "ezigbo" cholesterol, na obere njupụta lipoprotein (LDL), nke a na-akpọkarị "ọjọọ" cholesterol.
A na-ewere cholesterol HDL dị ka “dị mma” n'ihi na ọ na-enyere aka ikpochapụ oke LDL cholesterol n'ọbara wee bughachi ya na imeju, ebe enwere ike ịgbaji ma kpochapụ ya n'ahụ. LDL cholesterol, n'aka nke ọzọ, nwere ike na-ewuli elu n'ime akwara, na-akpụ plaque, na-emechi akwara na ibelata eruba ọbara. Nke a na-abawanye ohere nke ọrịa obi, ọrịa strok, na nsogbu obi ndị ọzọ.
Cholesterol dị elu n'ọbara bụ isi ihe na-ebute ọrịa obi, ihe na-ebute ọnwụ n'ụwa niile. Ọtụtụ ihe nwere ike ime ka cholesterol dị elu, gụnyere nri na-adịghị mma, enweghị mmega ahụ, ise siga, oke ibu, na ọnọdụ ahụike ụfọdụ, dị ka ọrịa shuga na hypothyroidism.
Iji chọpụta ọkwa cholesterol gị, a na-enyocha ọbara nke a na-akpọ profaịlụ lipid ma ọ bụ lipid panel. Nnwale a na-atụle mkpokọta cholesterol gị, LDL cholesterol, HDL cholesterol, na triglycerides (ụdị abụba ọzọ dị n'ọbara gị).
E nwere ụdị isi abụọ nke cholesterol: LDL na HDL
LDL cholesterol: LDL cholesterol na-anọchite anya lipoprotein dị obere ma mara ya dị ka "cholesterol" ọjọọ. Nke a bụ n'ihi na ọ nwere ike iduga n'ịkwalite plaque, ngwakọta nke abụba, kọlesterol na calcium nke nwere ike igbochi arteries na igbochi eruba ọbara. Mgbe egbochiri eruba ọbara, ị nwere ike ịnwe nkụchi obi ma ọ bụ ọrịa strok.
HDL cholesterol: HDL cholesterol pụtara lipoprotein dị elu. A na-akpọ ya "ezigbo" cholesterol n'ihi na HDL na-echebe obi. Ọrụ HDL bụ ibuga akụkụ LDL cholesterol site na obi gaa na imeju, ebe enwere ike ịpụ ya n'ahụ.
1. Ihe nri nri
Nri anyị na-ekere òkè dị mkpa n'ịchọpụta ọkwa cholesterol. Nri nwere abụba juru eju na abụba trans nwere ike ibute mmụba nke lipoprotein dị obere (LDL), nke a na-akpọkarị cholesterol "ọjọọ". Iri oke anụ uhie, ngwaahịa mmiri ara ehi nwere abụba buru ibu, nri e ghere eghe, nri a na-edozi nri, na achịcha achịcha nwere ike iduga n'ịkwalite LDL cholesterol, nke nwere ike igbochi akwara akwara ma gbochie oruru ọbara.
2. Ndụ ịnọ nkịtị
Enweghị mmega ahụ bụ isi ihe ọzọ na-ebute ọkwa cholesterol dị elu. Mmega ahụ mgbe niile na-enyere aka ịbawanye cholesterol dị elu nke lipoprotein (HDL), nke a na-akpọkarị "ezigbo" cholesterol, nke na-arụ ọrụ dị mkpa n'ibufe cholesterol karịrị ọbara n'imeju maka nhazi. Enweghị mmega ahụ zuru oke, nguzozi n'etiti LDL na HDL cholesterol nwere ike imebi, na-eme ka ọkwa cholesterol na-ebili.
3. Oke ibu na ibu ibu
Ibu oke ibu ma ọ bụ oke ibu nwere njikọ chiri anya na ọkwa cholesterol dị elu. Ibu oke ibu, ọkachasị gburugburu afọ, na-abawanye ọkwa LDL cholesterol na triglyceride ebe ọ na-ebelata cholesterol HDL. Ibu oke ibu na-emetụta ikike nke ahụ nwere ike metabolize nke ọma na iwepu cholesterol n'ọbara, na-eduga na mkpokọta cholesterol na mmepe nke atherosclerosis.
4. Ihe mkpụrụ ndụ ihe nketa
Ụfọdụ ndị mmadụ nwere ọchịchọ ebumpụta ụwa inwe ọkwa cholesterol dị elu n'ihi ọrịa mkpụrụ ndụ ihe nketa dị ka hypercholesterolemia ezinụlọ. Ọnọdụ ndị a na-akpaghasị ikike ahụ nwere ikpochapụ oke LDL cholesterol n'ọbara, na-eme ka ọkwa cholesterol dị elu na-adịgide adịgide. Ihe mkpụrụ ndụ ihe nketa na-akpata naanị pasentị ole na ole nke cholesterol dị elu, mana e kwesịghị ileghara ha anya mgbe a na-enyocha ihe ndị nwere ike ime mmadụ.
5. Ịṅụ sịga na ịṅụ mmanya
Ịṅụ sịga na ịṅụbiga mmanya ókè nwere ike imetụta ọkwa cholesterol dị njọ. Ịṅụ sịga na-ebelata cholesterol HDL, na-eme ka ọ ghara ịdị irè n'iwepụ LDL cholesterol n'ọbara. Ọ na-emebikwa mkpuchi nke akwara gị, na-eme ka ọ dịrị cholesterol mfe ịbanye n'ime ya wee mepụta plaque. N'aka nke ọzọ, ịṅụbiga mmanya ókè nwere ike ịkwalite ọkwa nke triglycerides, ụdị abụba dị n'ọbara nke e jikọtara ya na cholesterol dị elu.
1. Obi mgbu ma ọ bụ angina: Otu n'ime ihe ịrịba ama nke cholesterol dị elu bụ mgbu obi ma ọ bụ angina. Mgbe plaque na-ewuli elu n'ime akwara, ọ nwere ike igbochi ịgbasa ọbara na akwara obi, na-akpata mgbu obi ma ọ bụ ahụ erughị ala. Ihe mgbu a nwere ike ịpụta n'ime ogwe aka, ubu, olu, agba, ma ọ bụ azụ ma na-ebutekarị site na mgbatị anụ ahụ ma ọ bụ nrụgide mmetụta uche. Ọ bụrụ na ị nweta mgbaàmà ndị dị otú ahụ, ị ga-achọrịrị nlekọta ahụike ozugbo.
2. Oke ike ọgwụgwụ na adịghị ike: Ịda mbà n'obi mgbe niile ma ọ bụ adịghị ike n'enweghị ihe kpatara ya nwere ike ịbụ akara dị nro nke cholesterol dị elu. Mgbe akwara kpuchiri ya na ihe mgbakwasa plaque, ọ nwere ike igbochi eruba ọbara n'ime ahụ, na-akpata ike ọgwụgwụ na adịghị ike. Mgbaàmà ndị a nwere ike na-agaghị achọpụtakarị ma ọ bụ na-ekwu na ọ bụ n'ụdị ndụ na-adịghị arụ ọrụ ma ọ bụ enweghị ụra. Otú ọ dị, ọ dị mkpa ịṅa ntị na ihe ịrịba ama ndị a, n'ihi na ha nwere ike igosi nsogbu ahụike na-akpata, gụnyere nnukwu cholesterol.
3. Mkpirisi Ume: Ọ bụrụ na ị na-ahụ onwe gị ka ọ na-eku ume mgbe niile, ọbụlagodi n'oge ọrụ ọkụ ma ọ bụ na-ezu ike, ọ nwere ike ịkpata nchegbu. Ịkwalite plaque n'ime akwara nwere ike imetụta mgbasa ọbara na ngụgụ, na-eme ka ọ sie ike iku ume. Mgbaàmà a mgbe ụfọdụ na-eduga na nchọpụta na-ezighị ezi dị ka nsogbu iku ume kama inwe njikọ na cholesterol dị elu.
4. Ọbara mgbali elu: Ọbara mgbali elu, ma ọ bụ ọbara mgbali elu, na-ejikọta ya na ọkwa cholesterol dị elu. Ịkwalite plaque n'ime akwara ọ bụghị nanị na-egbochi ịgbasa ọbara, kamakwa ọ na-etinyekwu nrụgide n'obi, na-eme ka ọbara mgbali elu na-ebili. Ọ bụ ezie na ọbara mgbali elu nwere ike inwe ọtụtụ ihe kpatara ya, a ghaghị ịtụle ohere nke cholesterol dị elu dị ka ihe na-akpata ya.
5.N'ọnọdụ ndị a na-adịghị ahụkebe, ndị nwere cholesterol dị elu nwere ike ịmalite nkwụnye cholesterol dị nro, na-acha odo odo nke a na-akpọ xanthomas na akpụkpọ ahụ ha. Nkwụnye ego ndị a na-apụta n'ụzọ bụ isi na na gburugburu nku anya dị ka patches dị larịị, na-acha odo odo. Ọ bụ ezie na enweghị mgbu, ọnụnọ ha kwesịrị ime ka ndị mmadụ mara na enwere ike ịnwe ọkwa cholesterol dị elu.
Ịkwado ọkwa cholesterol dị mma dị mkpa maka ahụike zuru oke, n'ihi na ọkwa cholesterol dị elu nwere ike iduga n'ihe ize ndụ nke ọrịa obi na nsogbu ndị ọzọ nke obi. Ọ bụ ezie na ịnakwere ibi ndụ dị mma, gụnyere mmega ahụ mgbe niile na nri kwesịrị ekwesị, bụ ntọala nke ịchịkwa cholesterol, ụfọdụ ihe mgbakwunye nri nwekwara ike inye nkwalite dị ukwuu.
1. Omega-3 fatty acids
Omega-3 fatty acids, nke a na-ahụkarị na azụ ndị nwere abụba dị ka salmon, mackerel, na sardines, bụ ndị amara maka ọtụtụ uru ahụike ha. Ịtinye acids fatty a n'ime nri gị site na mgbakwunye ma ọ bụ iri azụ nwere ike inye aka belata ọkwa triglyceride na ịbawanye ọkwa HDL (ezigbo) cholesterol. Omega-3 fatty acids nwekwara ihe mgbochi mkpali nke na-enyere aka igbochi nhazi nke plaque n'ime akwara, na-enye aka na-eme ka ahụike obi dịkwuo mma.
2. Garlic
Ogologo oge ka amara garlic maka ọtụtụ uru ahụike ya, gụnyere ikike ọ nwere iwetu ọkwa cholesterol. Allicin, ihe na-arụ ọrụ na galik, ka egosiri na ọ na-ebelata mmepụta cholesterol n'ime imeju ma gbochie oxidation nke LDL cholesterol. Ịtinye galik raw ma ọ bụ sie ya na nri gị ma ọ bụ ị nweta ihe mgbakwunye galik nwere ike melite profaịlụ cholesterol gị, na-eme ka ọ dị mfe ma dị ọnụ ala mgbakwunye na atụmatụ nlekọta cholesterol gị.
OEA bụ ụmụ irighiri ihe na-eme n'ime ahụ anyị nke na-arụ ọrụ dị ka ihe na-egosi molekul maka usoro physiological dị iche iche. Ọ na-arụ ọrụ dị mkpa n'ịhazi nguzozi ike, agụụ, na metabolism lipid. A na-emepụta OEA na obere eriri afọ anyị, mana enwere ike ịhụ ya na akụkụ ahụ na anụ ahụ ndị ọzọ.
OEA nwere ike ịhazi ikike nke cholesterol metabolism. Ọtụtụ ọmụmụ egosila na OEA nwere ike imetụta ọkwa cholesterol site na-emetụta njikọ ya, njem ya, na absorption n'ime ahụ. Nnyocha e mere na ụdị anụmanụ egosila na nchịkwa OEA na-ebelata ọkwa cholesterol, kpọmkwem LDL (lipoprotein dị ala) cholesterol, cholesterol "ọjọọ".
OEA na-eme nke a site n'ịgbalite ụfọdụ ndị na-anabata nuklia n'ime eriri afọ, gụnyere PPAR-alpha (peroxisome proliferator-activated receptor alpha). Mgbe PPAR-alpha na-arụ ọrụ, ọ na-akpali ndakpọ nke acid fatty, si otú ahụ na-ebelata mmepụta cholesterol, karịsịa na imeju. Tụkwasị na nke ahụ, OEA nwere ike ime ka mpụ nke cholesterol dị n'ime ahụ dịkwuo elu, na-eme ka mmetụta ya na-ebelata cholesterol.
Na mgbakwunye, OEA na-eme ka mmetụta insulin dịkwuo mma ma na-achịkwa metabolism nke glucose, nke abụọ bụ isi ihe na-eme ka ọkwa cholesterol dị mma. Site n'ịhazi usoro metabolic ndị a, OEA na-akwalite profaịlụ lipid ahụike na-apụtaghị ìhè ma na-ebelata ihe ize ndụ nke nsogbu ndị metụtara cholesterol.
Cholesterol bụ abụba abụba nke ahụ anyị na-emepụta ma dịkwa na nri ụfọdụ. Ọ na-arụ ọrụ dị mkpa na ọrụ ahụ dị ka mmepụta nke homonụ na membranes cell.
Nnyocha na-egosi na PEA nwere ike igbochi mmepụta cholesterol na sel imeju. Site n'ime nke a, ọ nwere ike inye aka belata mkpokọta cholesterol ma belata ohere nke ọrịa obi. A na-eche na mmetụta cholesterol na-eweda ala nke PEA bụ n'ihi ikike ya ime ka ụfọdụ ndị na-anabata ya na-achịkwa metabolism nke cholesterol.
Ọzọkwa, a chọpụtala na PEA nwere ihe mgbochi mkpali. Mbufụt na-ekere òkè dị mkpa na mmepe nke atherosclerosis, ọrịa nke plaque cholesterol na-ewulite n'ime akwara, na-eme ka ọbara na-ebelata ma na-abawanye ohere nke ọrịa obi. Site na ibelata mbufụt, PEA nwere ike inye aka ịnọgide na-enwe akwara dị mma ma gbochie ịmalite cholesterol.
Ajụjụ: Ọgwụ ndị sitere n'okike ma ọ bụ mgbakwunye na-ebelata cholesterol nke ọma?
A: Ụfọdụ ọgwụgwọ sitere n'okike na mgbakwunye nwere ike inwe mmetụta na-ebelata cholesterol, mana ịdị irè ha dịgasị iche. A na-atụ aro ka ị kpọtụrụ onye ọkachamara ahụike tupu ịmalite ọgwụgwọ anụ ahụ ma ọ bụ mgbakwunye ọ bụla iji hụ na nchekwa na ịdị irè ha.
Ajụjụ: Ogologo oge ole ka ọ na-ewe iji hụ nsonaazụ sitere na mgbanwe ndụ wee belata cholesterol n'ụzọ nkịtị?
A: Usoro iheomume maka ịhụ nsonaazụ sitere na mgbanwe ndụ dịgasị iche site na mmadụ gaa na onye. Na mkpokọta, enwere ike ịhụ mmụba dị ịrịba ama na ọkwa cholesterol n'ime ọnwa 3 ruo 6 nke ime mgbanwe ndụ ahụike na-agbanwe agbanwe.
Disclaimer: Edemede a bụ naanị maka ozi izugbe na e kwesịghị ịkọwa ya dị ka ndụmọdụ ahụike ọ bụla. Ụfọdụ ozi biputere blọọgụ na-abịa site na ịntanetị na ọ bụghị ọkachamara. Webụsaịtị a na-ahụ maka nhazi, nhazi na idezi akụkọ. Ebumnuche nke ibuga ozi ndị ọzọ apụtaghị na ị kwenyere n'echiche ya ma ọ bụ kwado na ọdịnaya ya bụ eziokwu. Gakwuru onye ọkachamara ahụike mgbe niile tupu i jiri mgbakwunye ọ bụla ma ọ bụ mee mgbanwe na usoro nlekọta ahụike gị.
Oge nzipu: Nov-27-2023
