6-paradol bụ ngwakọta a na-ahụ na ginger. Ọ bụ ngwakọta sitere n'okike nke egosiri na ọ nwere uru ahụike. Edemede a ga-ekpuchi ihe niile ịchọrọ ịma gbasara 6-paradol yana otu ọ ga-esi baara ahụike gị uru.
- 6-paradol bụ akụkụ ekpomeekpo na-arụ ọrụ nke mkpụrụ nke ose Guinea (Aframomum melegueta ma ọ bụ ọka nke paradaịs). O sitere na klas nke kemịkalụ a maara dị ka alkylphenols, nke bụ ogige eke. 6-paradol, nke a na-etolitekarị site na 6-gingerol site na 6-gingerenol, bụ obere akụkụ nke ginger, yana dị ka phenol na-akpali akpali a na-ahụ na ezinụlọ ginger, a na-ahụ ya n'ọtụtụ osisi, gụnyere ginger, ose ojii na sesame, ma nwee ya. ọtụtụ ihe omume ndu. Ngwakọta bioactive a bụ isi iyi ụtọ pụrụ iche nke ginger na-egosi na ọ nwere ọtụtụ uru ahụike. Mgbe 6-Paradol na-ejikọta na saịtị cyclooxygenase (COX-2), ọ na-egbochi mmepe tumor nke ọma na ụmụ oke nwere ọrịa cancer anụ ahụ. 6-Paradol nwekwara ọtụtụ uru ahụike dị ka mgbochi mkpali, antioxidant, mgbochi oke ibu, ọbara mgbali elu na nkwalite ebe nchekwa.
Achọpụtara mmetụta nke 6-paradol na nnabata glucose na C2C12 myotubes (sel akwara) na 3T3-L1 adipocytes (sel abụba). Nsonaazụ gosiri na 6-paradol ọ bụghị naanị na ọ na-abawanye nnabata glucose na mkpụrụ ndụ abụọ ahụ, kamakwa ọ kwalitere ọrụ nke ụfọdụ protein iji kwalite nnabata glucose. Achọpụtakwara usoro akọwapụtara nke 6-paradol na-akwalite itinye glucose n'ọrụ. Nke mbụ, 6-paradol kwalitere ọrụ nke protein a na-akpọ AMPK. Protein a na-ahụ maka ịhazi metabolism ike na sel, yana site na ịgbalite AMPK, 6-paradol na-abawanye nnabata glucose cellular. Nnyocha ndị metụtara ya achọpụtala 6-paradol dị ka ebumnuche ọgwụgwọ nwere ike ịgwọ ọrịa shuga na oke ibu.
Yabụ, 6-paradol, dị ka ngwakọta eke, enwere ike iji ya na ebe ndị ahụ niile!
(1) Eji mee ihe dị ka ihe mgbakwunye nri
6-Paradol bụ ketone na-esi ísì ụtọ bụ isi iyi nke ọka nke Paradaịs ụtọ na ísì pụrụ iche. A na-eji ya na nkà mmụta ọgwụ ọdịnala kemgbe ọtụtụ narị afọ, a pụkwara iji ya mee ihe dị ka ihe na-esi ísì ụtọ na isi nri na ihe na-esi ísì ụtọ na ihe ọṅụṅụ. A na-achọta ya na ginger, ose ojii na mkpụrụ osisi sesame, ma bụrụkwa akụkụ nke ginger, mgbe ahụ enwere ike iji ya dị ka ihe mgbakwunye nri, mgbakwunye zuru oke na ndepụta ngwa nri nke nwere ike inye aka mee ka nri dịkwuo ụtọ na ụtọ. . N'ezie, enwere ike ịgbakwunye ọ bụghị naanị na nri, kamakwa na ihe ọṅụṅụ. E jiri ya tụnyere ihe mgbakwunye ndị ọzọ na-atọ ụtọ na ahịa, 6-parado bụ ihe okike, ya mere ọ bụ nhọrọ kachasị mma iji tinye ume na ụtọ na nri na ihe ọṅụṅụ.
(2) Ọ pụrụ inye aka melite mgbari mgbaze
Na ndụ, ọtụtụ mmadụ na-ata ahụhụ site na afọ ntachi na afọ erughị ala, yabụ ị nwere ike ịtụle 6-Paradol, otu n'ime mmetụta ya bụ inye aka na-agbaji na mgbari nri n'afọ, na mgbe a na-ejikọta ọnụ dị ka ihe mgbakwunye nri nwere ike ibelata ụfọdụ nsogbu mgbaze. ma n'ezie nsogbu ndị a abụghị naanị afọ ntachi na afọ ntachi dị ka e kwuru n'isiokwu ahụ, n'ihi na 6-Paradol nwere ihe mgbochi mkpali, nke nwere ike inye aka belata mbufụt na ahụ, nke nwere ike ibute ibu ibu na nsogbu ahụike ndị ọzọ. gụnyere afọ ntachi na ọgbụgbọ.
(3) Enwere ike imeziwanye nghọta
Uru ọzọ nke 6-paradol, bụ ikike ya iji melite ọrụ ọgụgụ isi. Nnyocha e mere egosiwo na 6-Paradol nwere ike inye aka kwalite ebe nchekwa na nlebara anya ma gbochie mbelata ọgụgụ isi metụtara afọ. 6-Paradol na-enyekwa aka ichebe mkpụrụ ndụ ụbụrụ site na mbufụt na antioxidants. Nke a na-enyere aka melite ahụike na ọrụ ogologo oge. Ihe na-arụ ọrụ ya, 6-gingerol, egosikwara na ọ na-akwalite ahụ ike nke etiti ahụ.
Nnyocha sayensị egosila na 6-Paradol nwere ọtụtụ mmetụta dị mma na ahụ. Mmetụta ndị a gụnyere:
(1) mgbochi mkpali
6-Paradol nwere ihe mgbochi mkpali dị ike nke na-arụ ọrụ nke ọma n'ịgwọ mbufụt na ahụ. Nnyocha egosiwo na ọ nwere ike igbochi mmepụta nke cytokines pro-inflammatory, bụ ndị na-ahụ maka mmepe nke mbufụt na-adịghị ala ala.
(2) Mmetụta mgbochi ọrịa kansa
Dị ka ọmụmụ si kwuo, 6-Paradol nwere ike igbochi uto mkpụrụ ndụ kansa n'ime ahụ. Ngwakọta a na-arụ ọrụ site n'inweta apoptosis, usoro nke na-eduga na ọnwụ nke mkpụrụ ndụ cancer.
(3) Mmetụta neuroprotective
Neuroprotection na-enyere aka ichebe usoro ụjọ mmadụ site na mmerụ ahụ ma ọ bụ mmebi nke usoro ahụike nwere ike ịkpata site na ọnọdụ ahụike nwere mmetụta nhụjuanya dị njọ. 6-Paradol nwere ihe neuroprotective nke na-enyere aka igbochi mmebi akwara ọzọ ma na-ebelata mmebi nke sistemu ụjọ nke etiti, nke nwere ike igbochi ọrịa akwara ozi dịka ọrịa Alzheimer.
(4) Mmetụta Antioxidant
6-Paradol nwere ikike antioxidant siri ike nke na-enyere aka belata mmebi oxidative n'ime ahụ. Ngwakọta bioactive a nwekwara ike igbochi ọrịa na ọnọdụ dị iche iche.
N'agbanyeghị onye ọ bụla, ọ dị ka ọ nweghị ụzọ ọzọ isi felata karịa mgbatị ahụ na iri nri. Dabere n'echiche a, ọ bụrụ na ịchọrọ ịkwụsị ibu, ịkwesịrị ịchịkwa ọnụ ọgụgụ calorie ị na-eri ma na-emega ahụ iji belata ọnụ ọgụgụ calorie na-adịghị mkpa, mana nsonaazụ ya nwere ike ọ gaghị apụta ìhè. Nnyocha egosiwo na otu n'ime uru ndị dị na 6-Paradol bụ ikike ya inye aka belata ibu, na 6-Paradol nwere ike inye aka na ọnwụ site na ịba ụba ume n'ime ahụ. Dị ka nnyocha e mere, a bioactive compound nwere ike ime ka ahụ okpomọkụ na ngwa ngwa metabolism, nke nwere ike butere abụba ọnwụ. Usoro a nwere ike inye aka mee ka metabolism dịkwuo elu ma mee ka calorie dịkwuo ọkụ, ọbụlagodi na ezumike. Nke a pụtara na site n'iji ya eme ihe, ịkwesighi ichegbu onwe gị maka mgbatị ahụ na nri. Ị nwere ike ghara ịma ihe ị na-eri na ole ị na-emega ahụ, mana ka na-abawanye nsonaazụ ọnwụ gị.
Ahụ na-echekwa abụba anụ ahụ na agba na ụdị abụọ, abụba ọcha na abụba aja aja. Abụba ọcha, nke a makwaara dị ka abụba visceral, bụ ụmụ irighiri mmiri lipid na rim dị mkpa nke nwere oghere na cytoplasm. Ọ na-agbakọta tumadi gburugburu afọ anyị; ebe abụba agba aja aja, nke a makwaara dị ka induced BAT, na-arụ ọrụ iji mezie okpomọkụ ahụ mgbe oyi na-atụ.
Enwere ọmụmụ ihe dị mkpa nke na-egosi na 6-paradol na-agbanwe anụ ahụ adipose ọcha ka ọ bụrụ anụ ahụ adipose na-acha aja aja, si otú a na-eme ka abụba na-agwụ ike echekwara dịkwuo maka ike. Na mgbakwunye, anụ ahụ adipose na-acha aja aja na-eji shuga ọbara na lipids, si otú a na-emeziwanye glucose metabolism na ọkwa lipid. Ya mere, ka ị na-enwekwu anụ ahụ adipose na-acha aja aja, otú ahụ ka abụba anụ ahụ ga-adị ka ume, si otú ahụ na-abawanye mmefu ike gị kwa ụbọchị.
Mmechi
N'ikpeazụ, 6-paradol bụ ihe dị ike nke dị na ginger. E gosiputara na ọ nwere mgbochi mkpali, mgbochi cancer, mgbochi oke ibu, antidiabetic, na neuroprotective Njirimara. A na-ewere ya dị mma iji rie ya. Ụzọ kacha mma ị ga-esi nweta 6-paradol bụ iji mgbakwunye. Agbanyeghị, tupu ị were mgbakwunye ọ bụla, ọ dị mkpa ịgwa dọkịta gị okwu.
Oge nzipu: Jun-07-2023
